FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124451906> ?p ?o ?g. }

• W2124451906 endingPage "16" @default.
• W2124451906 startingPage "7" @default.
• W2124451906 abstract "Open heart surgery with cardiopulmonary bypass is recognized as a common cause of acute kidney injury (AKI). The conventional biomarker creatinine is not sensitive enough to detect AKI until a significant decline in renal filtration has occurred. Urine neutrophil gelatinase-associated lipocalin (NGAL), part of an acute response to the release of tissue iron from cells, is an early biomarker and a predictor of AKI in a variety of clinical settings. We sought to evaluate the relationship between urine catalytic iron (unbound iron) and NGAL over the course of AKI due to cardiac surgery.FOURTEEN PATIENTS WHO UNDERWENT OPEN HEART SURGERY HAD THE FOLLOWING MEASURED: serum creatinine (0, 12, 24, 48 and 72 h postoperatively), urine NGAL and urine catalytic iron (0, 8, 24 and 48 h postoperatively). Urine NGAL and urine catalytic iron were quantified by immunoassay and bleomycin-detectable iron assay, respectively. AKI was defined by the Acute Kidney Injury Network (AKIN) criteria.Urine catalytic iron increased significantly (p < 0.05) within 8 h and peaked at 24 h postoperatively in patients who developed AKI (n = 8, baseline 101.96 ± 177.48, peak 226.35 ± 238.23 nmol/l, p = 0.006), but not in non-AKI patients (n = 6, baseline 131.08 ± 116.21, peak 163.99 ± 109.62 nmol/l, p = 0.380). Urine NGAL levels also peaked at 24 h with significant increase observed only in AKI patients: AKI - baseline 34.88 ± 26.47, peak 65.50 ± 27.03 ng/ml, p = 0.043; non-AKI - baseline 59.33 ± 31.72, peak 71.00 ± 31.76 ng/ml, p = 0.100. The correlation between baseline levels of urine catalytic iron and NGAL and peak levels of urine catalytic iron and NGAL was r = 0.86, p < 0.0001.Urine catalytic iron appears to rise and fall in concert with NGAL in patients undergoing cardiac surgery and may be indicative of early AKI. Future research into the role that catalytic iron plays in acute organ injury syndromes and its potential diagnostic and therapeutic implications is warranted." @default.
• W2124451906 created "2016-06-24" @default.
• W2124451906 creator A5008382551 @default.
• W2124451906 creator A5019759720 @default.
• W2124451906 creator A5030555505 @default.
• W2124451906 creator A5054456772 @default.
• W2124451906 creator A5058251507 @default.
• W2124451906 creator A5058930885 @default.
• W2124451906 creator A5071003499 @default.
• W2124451906 creator A5088137782 @default.
• W2124451906 date "2013-01-01" @default.
• W2124451906 modified "2023-10-13" @default.
• W2124451906 title "Urine Catalytic Iron and Neutrophil Gelatinase-Associated Lipocalin as Companion Early Markers of Acute Kidney Injury after Cardiac Surgery: A Prospective Pilot Study" @default.
• W2124451906 cites W149453202 @default.
• W2124451906 cites W1987181917 @default.
• W2124451906 cites W2002188125 @default.
• W2124451906 cites W2006245899 @default.
• W2124451906 cites W2013873227 @default.
• W2124451906 cites W2016900056 @default.
• W2124451906 cites W2020800955 @default.
• W2124451906 cites W2028875361 @default.
• W2124451906 cites W2032541391 @default.
• W2124451906 cites W2036681763 @default.
• W2124451906 cites W2037922200 @default.
• W2124451906 cites W2043185568 @default.
• W2124451906 cites W2045421375 @default.
• W2124451906 cites W2051933574 @default.
• W2124451906 cites W2056149198 @default.
• W2124451906 cites W2060226987 @default.
• W2124451906 cites W2061885883 @default.
• W2124451906 cites W2077424606 @default.
• W2124451906 cites W2094961600 @default.
• W2124451906 cites W2097478807 @default.
• W2124451906 cites W2098587662 @default.
• W2124451906 cites W2099006894 @default.
• W2124451906 cites W2108454749 @default.
• W2124451906 cites W2111753960 @default.
• W2124451906 cites W2113493898 @default.
• W2124451906 cites W2115560634 @default.
• W2124451906 cites W2116615296 @default.
• W2124451906 cites W2120503846 @default.
• W2124451906 cites W2122036831 @default.
• W2124451906 cites W2123277573 @default.
• W2124451906 cites W2124814686 @default.
• W2124451906 cites W2127253060 @default.
• W2124451906 cites W2131419242 @default.
• W2124451906 cites W2134272295 @default.
• W2124451906 cites W2136066292 @default.
• W2124451906 cites W2143262001 @default.
• W2124451906 cites W2144062408 @default.
• W2124451906 cites W2149687213 @default.
• W2124451906 cites W2152929995 @default.
• W2124451906 cites W2160691052 @default.
• W2124451906 cites W2161626134 @default.
• W2124451906 cites W2162400360 @default.
• W2124451906 cites W2164717104 @default.
• W2124451906 cites W2168092673 @default.
• W2124451906 cites W2169626783 @default.
• W2124451906 cites W3031149353 @default.
• W2124451906 cites W3149601801 @default.
• W2124451906 cites W41808191 @default.
• W2124451906 cites W82777057 @default.
• W2124451906 cites W2486913620 @default.
• W2124451906 doi "https://doi.org/10.1159/000346815" @default.
• W2124451906 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3743453" @default.
• W2124451906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23946721" @default.
• W2124451906 hasPublicationYear "2013" @default.
• W2124451906 type Work @default.
• W2124451906 sameAs 2124451906 @default.
• W2124451906 citedByCount "20" @default.
• W2124451906 countsByYear W21244519062014 @default.
• W2124451906 countsByYear W21244519062015 @default.
• W2124451906 countsByYear W21244519062016 @default.
• W2124451906 countsByYear W21244519062017 @default.
• W2124451906 countsByYear W21244519062019 @default.
• W2124451906 countsByYear W21244519062020 @default.
• W2124451906 countsByYear W21244519062023 @default.
• W2124451906 crossrefType "journal-article" @default.
• W2124451906 hasAuthorship W2124451906A5008382551 @default.
• W2124451906 hasAuthorship W2124451906A5019759720 @default.
• W2124451906 hasAuthorship W2124451906A5030555505 @default.
• W2124451906 hasAuthorship W2124451906A5054456772 @default.
• W2124451906 hasAuthorship W2124451906A5058251507 @default.
• W2124451906 hasAuthorship W2124451906A5058930885 @default.
• W2124451906 hasAuthorship W2124451906A5071003499 @default.
• W2124451906 hasAuthorship W2124451906A5088137782 @default.
• W2124451906 hasBestOaLocation W21244519061 @default.
• W2124451906 hasConcept C126322002 @default.
• W2124451906 hasConcept C126894567 @default.
• W2124451906 hasConcept C141071460 @default.
• W2124451906 hasConcept C159641895 @default.
• W2124451906 hasConcept C185592680 @default.
• W2124451906 hasConcept C20299238 @default.
• W2124451906 hasConcept C2778789114 @default.
• W2124451906 hasConcept C2778881276 @default.
• W2124451906 hasConcept C2780026642 @default.
• W2124451906 hasConcept C2780306776 @default.
• W2124451906 hasConcept C2780472472 @default.

• next