FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124458967> ?p ?o ?g. }

• W2124458967 endingPage "190" @default.
• W2124458967 startingPage "185" @default.
• W2124458967 abstract "Background: Leukemia inhibitory factor (LIF) is a pleiotropic cytokine of interleukin-6 family with a remarkable range of biological actions such as proliferative effects on the granulosa and theca cells. The aim of this study was to evaluate the effects of LIF on the growth and maturation of mouse fresh and vitrified preantral follicles, an in vitro model was developed. Methods: The ovaries of 14-day-old mice were vitrified in a mixture of ethylene glycol, ficoll 70 and sucrose in PB1 for 5 min. The preantral follicles were mechanically isolated from vitrified-warmed and non-vitrified ovaries. They were cultured in α-minimum essential medium supplemented with 5% fetal bovine serum, 100 mIU/ml recombinant follicle stimulating hormone, 1% insulin, transferrin and selenium, 20 ng/ml murine recombinant epidermal growth factor and different concentrations of LIF (25, 50, 100 ng/ml) for 12 days. On day 12, ovulation was induced using 1.5 mIU/ml human chorionic gonadotropin. In this study, the follicle diameter, survival rate and maturation rate were assessed. Results: The mean diameter of fresh and vitrified preantral follicles cultured in 50 ng/ml concentration of murine recombinant LIF was significantly higher than that of other concentrations in each group on day 2 (229.42 ± 30.40, 222.55 ± 33.4) (P<0.001) and on day 4 (340.45 ± 61.05, 299.50 ± 65.55), respectively (P<0.01). The survival rates of follicle in fresh and vitrified groups were 80.56% and 77.78, respectively. There was no significant difference between control and treated groups. The percentage of follicles which released metaphase II (MII) oocyte in fresh groups in the presence of 0, 25, 50, 100 ng/ml of LIF was 16%, 14.28%, 40% and 21.05% (P<0.01) and so in vitrified groups were 11.76%, 14.28%, 28.57% and 13.38%, respectively (P<0.05). There were significant differences between 50 ng/ml LIF-treated groups with other concentrations in each group. Conclusion: Therefore, in vitro growth and maturation of mouse preantral follicles were improved in the presence of 50 ng/ml LIF. Iran. Biomed. J. 10 (4): 185-190, 2006" @default.
• W2124458967 created "2016-06-24" @default.
• W2124458967 creator A5017737808 @default.
• W2124458967 creator A5025937848 @default.
• W2124458967 creator A5078300144 @default.
• W2124458967 creator A5082913782 @default.
• W2124458967 date "2006-10-15" @default.
• W2124458967 modified "2023-09-28" @default.
• W2124458967 title "The Effects of Different Concentrations of Leukemia Inhibitory Factor on the Development of Isolated Preantral Follicles from Fresh and Vitrified Mouse Ovaries" @default.
• W2124458967 cites W1838662971 @default.
• W2124458967 cites W1964214826 @default.
• W2124458967 cites W1965279413 @default.
• W2124458967 cites W1995176683 @default.
• W2124458967 cites W2000003232 @default.
• W2124458967 cites W2004090646 @default.
• W2124458967 cites W2005795262 @default.
• W2124458967 cites W2005958031 @default.
• W2124458967 cites W2010825213 @default.
• W2124458967 cites W2013876337 @default.
• W2124458967 cites W2018853148 @default.
• W2124458967 cites W2018933867 @default.
• W2124458967 cites W2020866505 @default.
• W2124458967 cites W2028967585 @default.
• W2124458967 cites W2029663217 @default.
• W2124458967 cites W2041633092 @default.
• W2124458967 cites W2046362747 @default.
• W2124458967 cites W2054410872 @default.
• W2124458967 cites W2075242594 @default.
• W2124458967 cites W2092464908 @default.
• W2124458967 cites W2095539949 @default.
• W2124458967 cites W2099469805 @default.
• W2124458967 cites W2108884230 @default.
• W2124458967 cites W2113243117 @default.
• W2124458967 cites W2122571320 @default.
• W2124458967 cites W2125318362 @default.
• W2124458967 cites W2128865345 @default.
• W2124458967 cites W2140444579 @default.
• W2124458967 cites W2149882128 @default.
• W2124458967 cites W2161105368 @default.
• W2124458967 cites W2163436394 @default.
• W2124458967 cites W2165917193 @default.
• W2124458967 cites W2470290731 @default.
• W2124458967 hasPublicationYear "2006" @default.
• W2124458967 type Work @default.
• W2124458967 sameAs 2124458967 @default.
• W2124458967 citedByCount "5" @default.
• W2124458967 crossrefType "journal-article" @default.
• W2124458967 hasAuthorship W2124458967A5017737808 @default.
• W2124458967 hasAuthorship W2124458967A5025937848 @default.
• W2124458967 hasAuthorship W2124458967A5078300144 @default.
• W2124458967 hasAuthorship W2124458967A5082913782 @default.
• W2124458967 hasConcept C102570824 @default.
• W2124458967 hasConcept C11988809 @default.
• W2124458967 hasConcept C126322002 @default.
• W2124458967 hasConcept C134018914 @default.
• W2124458967 hasConcept C137061746 @default.
• W2124458967 hasConcept C16685009 @default.
• W2124458967 hasConcept C175805485 @default.
• W2124458967 hasConcept C185592680 @default.
• W2124458967 hasConcept C202751555 @default.
• W2124458967 hasConcept C27284151 @default.
• W2124458967 hasConcept C2778690821 @default.
• W2124458967 hasConcept C5362183 @default.
• W2124458967 hasConcept C55493867 @default.
• W2124458967 hasConcept C71924100 @default.
• W2124458967 hasConcept C86803240 @default.
• W2124458967 hasConceptScore W2124458967C102570824 @default.
• W2124458967 hasConceptScore W2124458967C11988809 @default.
• W2124458967 hasConceptScore W2124458967C126322002 @default.
• W2124458967 hasConceptScore W2124458967C134018914 @default.
• W2124458967 hasConceptScore W2124458967C137061746 @default.
• W2124458967 hasConceptScore W2124458967C16685009 @default.
• W2124458967 hasConceptScore W2124458967C175805485 @default.
• W2124458967 hasConceptScore W2124458967C185592680 @default.
• W2124458967 hasConceptScore W2124458967C202751555 @default.
• W2124458967 hasConceptScore W2124458967C27284151 @default.
• W2124458967 hasConceptScore W2124458967C2778690821 @default.
• W2124458967 hasConceptScore W2124458967C5362183 @default.
• W2124458967 hasConceptScore W2124458967C55493867 @default.
• W2124458967 hasConceptScore W2124458967C71924100 @default.
• W2124458967 hasConceptScore W2124458967C86803240 @default.
• W2124458967 hasIssue "4" @default.
• W2124458967 hasLocation W21244589671 @default.
• W2124458967 hasOpenAccess W2124458967 @default.
• W2124458967 hasPrimaryLocation W21244589671 @default.
• W2124458967 hasRelatedWork W1493990508 @default.
• W2124458967 hasRelatedWork W190592619 @default.
• W2124458967 hasRelatedWork W1986550324 @default.
• W2124458967 hasRelatedWork W2000003232 @default.
• W2124458967 hasRelatedWork W2005795262 @default.
• W2124458967 hasRelatedWork W2011873884 @default.
• W2124458967 hasRelatedWork W2047527040 @default.
• W2124458967 hasRelatedWork W2093313776 @default.
• W2124458967 hasRelatedWork W2107847773 @default.
• W2124458967 hasRelatedWork W2111233069 @default.
• W2124458967 hasRelatedWork W2120344978 @default.
• W2124458967 hasRelatedWork W2136932385 @default.
• W2124458967 hasRelatedWork W2150300042 @default.

• next