FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124561991> ?p ?o ?g. }

• W2124561991 endingPage "41" @default.
• W2124561991 startingPage "25" @default.
• W2124561991 abstract "Tissue homeostasis is determined by a balance between proliferation and apoptosis. Various lesions in the brain are accompanied by proliferation and subsequent death of glial cells, but the mechanisms that limit this expansion of glial populations remains unknown. One possible candidate is the death ligand, FasL, and its receptor Fas, because the expression of both proteins was reported on glial cells. To elucidate the expression and putative function of Fas and FasL on proliferative glial cells, we performed stereotactic lesion of the entorhinal cortex of adult rats. Such lesions induce proliferation of astrocytes and microglial cells in the hippocampal fields of anterograde degeneration. Subsequently, the total number of both cell types returns to pre-lesion counts. We found that Fas and FasL is strongly upregulated on astrocytes in the zone of anterograde degeneration with a peak 5 days postlesion (dpl) and a return to control levels at 10 dpl. However, evidence for astrocytic cell death was neither detected by TUNEL staining, immunocytochemistry for c-Jun, and apoptosis-specific protein (ASP), nor by staining for morphologic hallmarks of apoptotic or necrotic cell death at the light and electron microscopic level. Thus, increased expression of Fas and FasL is not accompanied by cell death of reactive astrocytes during anterograde degeneration." @default.
• W2124561991 created "2016-06-24" @default.
• W2124561991 creator A5022920379 @default.
• W2124561991 creator A5025301587 @default.
• W2124561991 creator A5027512978 @default.
• W2124561991 creator A5063708769 @default.
• W2124561991 creator A5065116801 @default.
• W2124561991 creator A5088903979 @default.
• W2124561991 date "2000-01-01" @default.
• W2124561991 modified "2023-10-18" @default.
• W2124561991 title "Reactive astrocytes upregulate fas (CD95) and fas ligand (CD95L) expression but do not undergo programmed cell death during the course of anterograde degeneration" @default.
• W2124561991 cites W1539984014 @default.
• W2124561991 cites W1564489838 @default.
• W2124561991 cites W1593600686 @default.
• W2124561991 cites W1651324749 @default.
• W2124561991 cites W1739127553 @default.
• W2124561991 cites W18702381 @default.
• W2124561991 cites W1945522850 @default.
• W2124561991 cites W1951599209 @default.
• W2124561991 cites W1964991198 @default.
• W2124561991 cites W1966101204 @default.
• W2124561991 cites W1967271126 @default.
• W2124561991 cites W1971054448 @default.
• W2124561991 cites W1971668430 @default.
• W2124561991 cites W1974408875 @default.
• W2124561991 cites W1976702427 @default.
• W2124561991 cites W1976868133 @default.
• W2124561991 cites W1978897896 @default.
• W2124561991 cites W1980516488 @default.
• W2124561991 cites W1982804078 @default.
• W2124561991 cites W1984035321 @default.
• W2124561991 cites W1992060545 @default.
• W2124561991 cites W1993199753 @default.
• W2124561991 cites W1995644527 @default.
• W2124561991 cites W1997951257 @default.
• W2124561991 cites W1999075359 @default.
• W2124561991 cites W2003285575 @default.
• W2124561991 cites W2004241753 @default.
• W2124561991 cites W2004645606 @default.
• W2124561991 cites W2005770035 @default.
• W2124561991 cites W2009588334 @default.
• W2124561991 cites W2017840093 @default.
• W2124561991 cites W2019808903 @default.
• W2124561991 cites W2025554920 @default.
• W2124561991 cites W2029377803 @default.
• W2124561991 cites W2041466047 @default.
• W2124561991 cites W2043639971 @default.
• W2124561991 cites W2044092316 @default.
• W2124561991 cites W2057289234 @default.
• W2124561991 cites W2059473240 @default.
• W2124561991 cites W2065569093 @default.
• W2124561991 cites W2081201017 @default.
• W2124561991 cites W2083422282 @default.
• W2124561991 cites W2084248168 @default.
• W2124561991 cites W2087781170 @default.
• W2124561991 cites W2088590507 @default.
• W2124561991 cites W2096396515 @default.
• W2124561991 cites W2098553579 @default.
• W2124561991 cites W2105037115 @default.
• W2124561991 cites W2109095345 @default.
• W2124561991 cites W2118821335 @default.
• W2124561991 cites W2136130185 @default.
• W2124561991 cites W2141487162 @default.
• W2124561991 cites W2141850990 @default.
• W2124561991 cites W2142925815 @default.
• W2124561991 cites W2147122201 @default.
• W2124561991 cites W2148894882 @default.
• W2124561991 cites W2157645771 @default.
• W2124561991 cites W2160838897 @default.
• W2124561991 cites W2160875934 @default.
• W2124561991 cites W2168603084 @default.
• W2124561991 cites W2169366153 @default.
• W2124561991 cites W2315182483 @default.
• W2124561991 cites W4231829827 @default.
• W2124561991 cites W4294115345 @default.
• W2124561991 cites W4313341495 @default.
• W2124561991 doi "https://doi.org/10.1002/1098-1136(200010)32:1<25::aid-glia30>3.0.co;2-y" @default.
• W2124561991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10975908" @default.
• W2124561991 hasPublicationYear "2000" @default.
• W2124561991 type Work @default.
• W2124561991 sameAs 2124561991 @default.
• W2124561991 citedByCount "57" @default.
• W2124561991 countsByYear W21245619912012 @default.
• W2124561991 countsByYear W21245619912013 @default.
• W2124561991 countsByYear W21245619912014 @default.
• W2124561991 countsByYear W21245619912015 @default.
• W2124561991 countsByYear W21245619912016 @default.
• W2124561991 countsByYear W21245619912022 @default.
• W2124561991 crossrefType "journal-article" @default.
• W2124561991 hasAuthorship W2124561991A5022920379 @default.
• W2124561991 hasAuthorship W2124561991A5025301587 @default.
• W2124561991 hasAuthorship W2124561991A5027512978 @default.
• W2124561991 hasAuthorship W2124561991A5063708769 @default.
• W2124561991 hasAuthorship W2124561991A5065116801 @default.
• W2124561991 hasAuthorship W2124561991A5088903979 @default.
• W2124561991 hasConcept C104317684 @default.
• W2124561991 hasConcept C127561419 @default.
• W2124561991 hasConcept C142724271 @default.

• next