FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124690429> ?p ?o ?g. }

• W2124690429 endingPage "403" @default.
• W2124690429 startingPage "403" @default.
• W2124690429 abstract "ContextOmega-3 fatty acids are purported to reduce the risk of cancer. Studies have reported mixed results.ObjectiveTo synthesize published and unpublished evidence to determine estimates of the effect of omega-3 fatty acids on cancer risk in prospective cohort studies.Data SourcesArticles published from 1966 to October 2005 identified through MEDLINE, PREMEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and CAB Health; unpublished literature sought through letters to experts in the neutraceutical industry.Study SelectionA total of 38 articles with a description of effects of consumption of omega-3 fatty acids on tumor incidence, prospective cohort study design, human study population; and description of effect of omega-3 among groups with different levels of exposure in the cohort were included. Two reviewers independently reviewed articles using structured abstraction forms; disagreements were resolved by consensus.Data ExtractionTwo reviewers independently abstracted detailed data about the incidence of cancer, the type of cancer, the number and characteristics of the patients, details on the exposure to omega-3 fatty acids, and the elapsed time between the intervention and outcome measurements. Data about the methodological quality of the study were also abstracted.Data SynthesisAcross 20 cohorts from 7 countries for 11 different types of cancer and using up to 6 different ways to categorize omega-3 fatty acid consumption, 65 estimates of the association between omega-3 fatty acid consumption were reported. Among these, only 8 were statistically significant. The high degree of heterogeneity across these studies precluded pooling of data. For breast cancer 1 significant estimate was for increased risk (incidence risk ratio [IRR], 1.47; 95% confidence interval [CI], 1.10-1.98) and 3 were for decreased risk (RR, 0.68-0.72); 7 other estimates did not show a significant association. For colorectal cancer, there was 1 estimate of decreased risk (RR, 0.49; 95% CI, 0.27-0.89) and 17 estimates without association. For lung cancer one of the significant associations was for increased cancer risk (IRR, 3.0; 95% CI, 1.2-7.3), the other was for decreased risk (RR, 0.32; 95% CI, 0.13-0.76), and 4 other estimates were not significant. For prostate cancer, there was 1 estimate of decreased risk (RR, 0.43; 95% CI, 0.22-0.83) and 1 of increased risk (RR, 1.98; 95% CI, 1.34-2.93) for advanced prostate cancer; 15 other estimates did not show a significant association. The study that assessed skin cancer found an increased risk (RR, 1.13; 95% CI, 1.01-1.27). No significant associations between omega-3 fatty acid consumption and cancer incidence were found for aerodigestive cancer, bladder cancer, lymphoma, ovarian cancer, pancreatic cancer, or stomach cancer.ConclusionsA large body of literature spanning numerous cohorts from many countries and with different demographic characteristics does not provide evidence to suggest a significant association between omega-3 fatty acids and cancer incidence. Dietary supplementation with omega-3 fatty acids is unlikely to prevent cancer." @default.
• W2124690429 created "2016-06-24" @default.
• W2124690429 creator A5007536032 @default.
• W2124690429 creator A5008535622 @default.
• W2124690429 creator A5032703149 @default.
• W2124690429 creator A5036509896 @default.
• W2124690429 creator A5040277799 @default.
• W2124690429 creator A5045104164 @default.
• W2124690429 creator A5056237707 @default.
• W2124690429 creator A5058146707 @default.
• W2124690429 creator A5067416350 @default.
• W2124690429 creator A5087854820 @default.
• W2124690429 creator A5089460885 @default.
• W2124690429 date "2006-01-25" @default.
• W2124690429 modified "2023-10-17" @default.
• W2124690429 title "Effects of Omega-3 Fatty Acids on Cancer Risk" @default.
• W2124690429 cites W111439174 @default.
• W2124690429 cites W1847371803 @default.
• W2124690429 cites W1974630591 @default.
• W2124690429 cites W1978412772 @default.
• W2124690429 cites W1978447671 @default.
• W2124690429 cites W1981684704 @default.
• W2124690429 cites W1986215651 @default.
• W2124690429 cites W1986235434 @default.
• W2124690429 cites W1992707361 @default.
• W2124690429 cites W1997399062 @default.
• W2124690429 cites W2000797436 @default.
• W2124690429 cites W2001494923 @default.
• W2124690429 cites W2003567705 @default.
• W2124690429 cites W2004946088 @default.
• W2124690429 cites W2006280650 @default.
• W2124690429 cites W2030856838 @default.
• W2124690429 cites W2034958306 @default.
• W2124690429 cites W2036997090 @default.
• W2124690429 cites W2042346472 @default.
• W2124690429 cites W2045287303 @default.
• W2124690429 cites W2053454686 @default.
• W2124690429 cites W2055985695 @default.
• W2124690429 cites W2056244142 @default.
• W2124690429 cites W2058123599 @default.
• W2124690429 cites W2060201243 @default.
• W2124690429 cites W2068781555 @default.
• W2124690429 cites W2071956733 @default.
• W2124690429 cites W2073412226 @default.
• W2124690429 cites W2074115218 @default.
• W2124690429 cites W2076808830 @default.
• W2124690429 cites W2079556277 @default.
• W2124690429 cites W2080210880 @default.
• W2124690429 cites W2087241340 @default.
• W2124690429 cites W2088576316 @default.
• W2124690429 cites W2089655567 @default.
• W2124690429 cites W2089877079 @default.
• W2124690429 cites W2102512178 @default.
• W2124690429 cites W2108381090 @default.
• W2124690429 cites W2112772855 @default.
• W2124690429 cites W2114488753 @default.
• W2124690429 cites W2116541931 @default.
• W2124690429 cites W2120533008 @default.
• W2124690429 cites W2123021630 @default.
• W2124690429 cites W2124141491 @default.
• W2124690429 cites W2126032075 @default.
• W2124690429 cites W2130015261 @default.
• W2124690429 cites W2141384435 @default.
• W2124690429 cites W2146331685 @default.
• W2124690429 cites W2147050953 @default.
• W2124690429 cites W2147687079 @default.
• W2124690429 cites W2148119266 @default.
• W2124690429 cites W2149160757 @default.
• W2124690429 cites W2150392477 @default.
• W2124690429 cites W2160329810 @default.
• W2124690429 cites W2162737599 @default.
• W2124690429 cites W2166481344 @default.
• W2124690429 cites W2172186515 @default.
• W2124690429 cites W2236108009 @default.
• W2124690429 cites W2330504627 @default.
• W2124690429 cites W2399979872 @default.
• W2124690429 doi "https://doi.org/10.1001/jama.295.4.403" @default.
• W2124690429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16434631" @default.
• W2124690429 hasPublicationYear "2006" @default.
• W2124690429 type Work @default.
• W2124690429 sameAs 2124690429 @default.
• W2124690429 citedByCount "456" @default.
• W2124690429 countsByYear W21246904292012 @default.
• W2124690429 countsByYear W21246904292013 @default.
• W2124690429 countsByYear W21246904292014 @default.
• W2124690429 countsByYear W21246904292015 @default.
• W2124690429 countsByYear W21246904292016 @default.
• W2124690429 countsByYear W21246904292017 @default.
• W2124690429 countsByYear W21246904292018 @default.
• W2124690429 countsByYear W21246904292019 @default.
• W2124690429 countsByYear W21246904292020 @default.
• W2124690429 countsByYear W21246904292021 @default.
• W2124690429 countsByYear W21246904292022 @default.
• W2124690429 countsByYear W21246904292023 @default.
• W2124690429 crossrefType "journal-article" @default.
• W2124690429 hasAuthorship W2124690429A5007536032 @default.
• W2124690429 hasAuthorship W2124690429A5008535622 @default.
• W2124690429 hasAuthorship W2124690429A5032703149 @default.

• next