FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2124697776> ?p ?o ?g. }

• W2124697776 endingPage "30" @default.
• W2124697776 startingPage "25" @default.
• W2124697776 abstract "The docetaxel and gemcitabine combination is an active regimen as salvage therapy in taxane-resistant or taxane-refractory patients with metastatic breast cancer (MBC). We recently conducted a phase II study administering this combination to patients with MBC after docetaxel failure, with remarkably high response rates that could be attributed to an in vivo synergism between the two drugs. Women with MBC who were refractory or resistant to docetaxel monotherapy as first- or second-line treatment were recruited. Patients with progressive or stable disease after receiving a minimum of four cycles of docetaxel received gemcitabine 900 mg/m2 on days 1 and 8 plus docetaxel 100 mg/m2on day 8, every 3 weeks. Forty-six percent of patients responded (three complete responses, 20 partial responses), while 28% had stable disease and 26% had progressive disease. Median duration of response was 6.07 ± 2.43 months. Neutropenia was the only grade 4 toxicity, and reported in seven patients. Other grade 3 toxicities included neutropenia (12 patients), thrombocytopenia (seven patients), and anemia (one patient), while nonhematologic toxicities were easily manageable. These data outline the importance of a rational combination of existing, active chemotherapeutic agents for MBC, and broadens our perspectives for more effective combination regimens in various solid tumors in the future." @default.
• W2124697776 created "2016-06-24" @default.
• W2124697776 creator A5052189975 @default.
• W2124697776 creator A5059430071 @default.
• W2124697776 creator A5079973181 @default.
• W2124697776 date "2004-04-01" @default.
• W2124697776 modified "2023-10-17" @default.
• W2124697776 title "In vivo synergism between docetaxel and gemcitabine in patients with metastatic breast cancer: General concepts and future perspectives" @default.
• W2124697776 cites W1522557416 @default.
• W2124697776 cites W1812067939 @default.
• W2124697776 cites W1907604566 @default.
• W2124697776 cites W1955744924 @default.
• W2124697776 cites W1966512548 @default.
• W2124697776 cites W1969645708 @default.
• W2124697776 cites W1971473564 @default.
• W2124697776 cites W1972888300 @default.
• W2124697776 cites W1976487179 @default.
• W2124697776 cites W1985807450 @default.
• W2124697776 cites W1985904021 @default.
• W2124697776 cites W1991211039 @default.
• W2124697776 cites W2014134856 @default.
• W2124697776 cites W2028117648 @default.
• W2124697776 cites W2045316633 @default.
• W2124697776 cites W2047744168 @default.
• W2124697776 cites W2047796892 @default.
• W2124697776 cites W2073207494 @default.
• W2124697776 cites W2075855978 @default.
• W2124697776 cites W2076675372 @default.
• W2124697776 cites W2078003564 @default.
• W2124697776 cites W2095540788 @default.
• W2124697776 cites W2112875040 @default.
• W2124697776 cites W2119097396 @default.
• W2124697776 cites W2126942676 @default.
• W2124697776 cites W2129979963 @default.
• W2124697776 cites W2131770017 @default.
• W2124697776 cites W2133208325 @default.
• W2124697776 cites W2150067367 @default.
• W2124697776 cites W2158193797 @default.
• W2124697776 cites W2164208194 @default.
• W2124697776 cites W2171875712 @default.
• W2124697776 cites W2176579253 @default.
• W2124697776 cites W2314318352 @default.
• W2124697776 cites W2329401292 @default.
• W2124697776 cites W4214660454 @default.
• W2124697776 cites W4235117882 @default.
• W2124697776 cites W4240199695 @default.
• W2124697776 cites W4241852612 @default.
• W2124697776 cites W4245082910 @default.
• W2124697776 cites W4253716410 @default.
• W2124697776 doi "https://doi.org/10.1053/j.seminoncol.2004.03.024" @default.
• W2124697776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15199529" @default.
• W2124697776 hasPublicationYear "2004" @default.
• W2124697776 type Work @default.
• W2124697776 sameAs 2124697776 @default.
• W2124697776 citedByCount "4" @default.
• W2124697776 countsByYear W21246977762021 @default.
• W2124697776 crossrefType "journal-article" @default.
• W2124697776 hasAuthorship W2124697776A5052189975 @default.
• W2124697776 hasAuthorship W2124697776A5059430071 @default.
• W2124697776 hasAuthorship W2124697776A5079973181 @default.
• W2124697776 hasConcept C121608353 @default.
• W2124697776 hasConcept C126322002 @default.
• W2124697776 hasConcept C141071460 @default.
• W2124697776 hasConcept C143998085 @default.
• W2124697776 hasConcept C2775930923 @default.
• W2124697776 hasConcept C2776694085 @default.
• W2124697776 hasConcept C2777063308 @default.
• W2124697776 hasConcept C2777511904 @default.
• W2124697776 hasConcept C2778822529 @default.
• W2124697776 hasConcept C2780258809 @default.
• W2124697776 hasConcept C2781190966 @default.
• W2124697776 hasConcept C2781413609 @default.
• W2124697776 hasConcept C530470458 @default.
• W2124697776 hasConcept C71924100 @default.
• W2124697776 hasConceptScore W2124697776C121608353 @default.
• W2124697776 hasConceptScore W2124697776C126322002 @default.
• W2124697776 hasConceptScore W2124697776C141071460 @default.
• W2124697776 hasConceptScore W2124697776C143998085 @default.
• W2124697776 hasConceptScore W2124697776C2775930923 @default.
• W2124697776 hasConceptScore W2124697776C2776694085 @default.
• W2124697776 hasConceptScore W2124697776C2777063308 @default.
• W2124697776 hasConceptScore W2124697776C2777511904 @default.
• W2124697776 hasConceptScore W2124697776C2778822529 @default.
• W2124697776 hasConceptScore W2124697776C2780258809 @default.
• W2124697776 hasConceptScore W2124697776C2781190966 @default.
• W2124697776 hasConceptScore W2124697776C2781413609 @default.
• W2124697776 hasConceptScore W2124697776C530470458 @default.
• W2124697776 hasConceptScore W2124697776C71924100 @default.
• W2124697776 hasLocation W21246977761 @default.
• W2124697776 hasLocation W21246977762 @default.
• W2124697776 hasOpenAccess W2124697776 @default.
• W2124697776 hasPrimaryLocation W21246977761 @default.
• W2124697776 hasRelatedWork W2046196715 @default.
• W2124697776 hasRelatedWork W2067939746 @default.
• W2124697776 hasRelatedWork W2101100140 @default.
• W2124697776 hasRelatedWork W2114282601 @default.
• W2124697776 hasRelatedWork W2151941897 @default.
• W2124697776 hasRelatedWork W2347099117 @default.

• next