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• W2124700539 abstract "The reaction of 6-aminopyrimidin-4-ones 1 with benzaldehydes 2 and β-aminocrotononitrile 3 or benzoylacetonitrile 4 under microwave irradiation in dry media yields the 6-cyano-5,8-dihydropyrido[2,3-d]-pyrimidinones 5a-t. The structure of the synthesized compounds was determined on the basis of nmr measurements, especially by 1H,1H−, 1H,13C COSY, DEPT and NOESY experiments. In contrast with other pyrido-[2,3-d]pyrimidine derivatives, these compounds did not show any antifungal in vitro activity up to 250 μg/mL." @default.
• W2124700539 created "2016-06-24" @default.
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• W2124700539 date "2006-03-01" @default.
• W2124700539 modified "2023-09-29" @default.
• W2124700539 title "Microwave-assisted three-component synthesis and<i>in vitro</i>antifungal evaluation of 6-cyano-5,8-dihydropyrido[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-ones" @default.
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• W2124700539 doi "https://doi.org/10.1002/jhet.5570430208" @default.
• W2124700539 hasPublicationYear "2006" @default.
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