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- W2124894648 abstract "There is a large body of evidence suggesting that cholinergic activity is involved in memory processes. It seems that cholinergic activity is essential to learn several tasks and recent works suggest that acetylcholine plays an important role during the early stages of memory formation. In this review, we will discuss the results related to taste memory formation, focusing particularly on the conditioned taste aversion paradigm. We will first give evidence that nucleus basalis magnocellularis is involved in taste memory formation, due to its cholinergic projections. We then show that the cholinergic activity of the insular (gustatory) cortex is related to the taste novelty, and that the cholinergic signals initiated by novelty are crucial for taste memory formation. Then we present recent data indicating that cortical activation of muscarinic receptors is necessary for taste trace encoding, and also for its consolidation under certain circumstances. Finally, interactions between the cholinergic and other neuromodulatory systems inducing intracellular mechanisms related to plastic changes will be proposed as important processes underlying gustatory memory trace storage." @default.
- W2124894648 created "2016-06-24" @default.
- W2124894648 creator A5002775152 @default.
- W2124894648 date "2003-11-01" @default.
- W2124894648 modified "2023-10-16" @default.
- W2124894648 title "Role of cholinergic system on the construction of memories: Taste memory encoding" @default.
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- W2124894648 doi "https://doi.org/10.1016/s1074-7427(03)00061-3" @default.
- W2124894648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14521864" @default.
- W2124894648 hasPublicationYear "2003" @default.
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