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- W2124907773 abstract "Atherosclerosis is accompanied by a low grade inflammatory response.To use erythrocyte aggregability as a biomarker to exclude the presence of low grade inflammatory response in apparently healthy individuals.The adhesiveness/aggregation of red blood cells was quantitated by using a simple slide test and image analysis.We included 121 apparently healthy individuals and found a significant correlation between the degree of erythrocyte adhesiveness/aggregation and either the concentration of high sensitive CRP (r = 0.6, P < 0.001), erythrocyte sedimentation rate (r = 0.5, P < 0.0001) or fibrinogen (r = 0.5, P < 0.0001). By using certain cutoff points for the erythrocyte adhesiveness/aggregation test we could define individuals with a very low grade inflammatory response.By using this inexpensive and rapid assessment, we could clearly discriminate between individuals with a very low inflammatory response and those with a more intense one. This biomarker should be further evaluated as a possible screening test for use in large populations of apparently healthy individuals in whom the detection of low grade inflammation might contribute to guiding appropriate lifestyle modifications and therapeutic interventions." @default.
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- W2124907773 date "2002-10-01" @default.
- W2124907773 modified "2023-09-27" @default.
- W2124907773 title "A Simple Biomarker to Exclude the Presence of Low Grade Inflammation in Apparently Healthy Individuals" @default.
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- W2124907773 doi "https://doi.org/10.1177/174182670200900509" @default.
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