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- W212492127 abstract "Surface membrane glycoproteins of tumor cells contain glycopeptides characteristic of transformed fibroblasts and epithelial cells. Loosely associated and more intrinsic membrane glycoproteins of transformed cells, metabolically labeled, show striking differences in the specific activity of the hydrolyzable fucose residues. Pronase digestion and chromatographic purification separate four fucose-containing glycopeptides unique for transformed cells from three common to normal and transformed cells. One transformation-specific glycopeptide, which has been sequenced by treatment with exoglycosidases and quantitation of the released monosaccharides, contains three oligosaccharide branches, each terminating in sialic acid. The core contains β-D-mannose and α-L-fucose. The putative structure is given and reinforces previous suggestions that transformation specific glycopeptides are more complex than those from normal cells." @default.
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- W212492127 title "SURFACE MEMBRANES OF TUMOR CELLS" @default.
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- W212492127 doi "https://doi.org/10.1016/b978-0-12-326150-2.50008-0" @default.
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