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- W2125015093 endingPage "126" @default.
- W2125015093 startingPage "117" @default.
- W2125015093 abstract "Photoacoustic imaging (PAI), providing the unique contrast of optical absorption and the superb scalability of spatial resolution and penetration, has emerged as an enabling technique in both basic and translational brain research. In this paper, first, mechanisms behind neuro-PAI of endogenous absorber-encoded functional information (e.g., the concentration of hemoglobin, the oxygen saturation of hemoglobin, blood flow, oxygen metabolism, and water accumulation) and exogenous probe-labeled molecular targets (e.g., neural activity, glucose uptake, aberrant protein aggregation, and malignancy) are introduced. Then, two technical innovations—functional connectivity photoacoustic tomography and high-speed functional photoacoustic microscopy—for spatio-temporal interrogation of the brain at resting and activated states are highlighted, and two application niches in vascular cognitive impairment and brain cancer are discussed. Finally, the prospect of neuro-PAI is envisioned." @default.
- W2125015093 created "2016-06-24" @default.
- W2125015093 creator A5021143013 @default.
- W2125015093 date "2016-05-01" @default.
- W2125015093 modified "2023-10-17" @default.
- W2125015093 title "Listening to the Brain With Photoacoustics" @default.
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