FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125096269> ?p ?o ?g. }

• W2125096269 endingPage "3090" @default.
• W2125096269 startingPage "3084" @default.
• W2125096269 abstract "ABSTRACT The resistance of Acinetobacter baumannii strains to carbapenems is a worrying problem in hospital settings. The main mechanism of carbapenem resistance is the expression of β-lactamases (metalloenzymes or class D enzymes). The mechanisms of the dissemination of these genes among A. baumannii strains are not fully understood. In this study we used two carbapenem-resistant clinical strains of A. baumannii (AbH12O-A2 and AbH12O-CU3) expressing the plasmid-borne bla OXA-24 gene (plasmids pMMA2 and pMMCU3, respectively) to demonstrate that A. baumannii releases outer membrane vesicles (OMVs) during in vitro growth. The use of hybridization studies enabled us to show that these OMVs harbored the bla OXA-24 gene. The incubation of these OMVs with the carbapenem-susceptible A. baumannii ATCC 17978 host strain yielded full resistance to carbapenems. The presence of the original plasmids harboring the bla OXA-24 gene was detected in strain ATCC 17978 after the transformation of OMVs. New OMVs harboring bla OXA-24 were released by A. baumannii ATCC 17978 after it was transformed with the original OMV-mediated plasmids, indicating the universality of the process. We present the first experimental evidence that clinical isolates of A. baumannii may release OMVs as a mechanism of horizontal gene transfer whereby carbapenem resistance genes are delivered to surrounding A. baumannii bacterial isolates." @default.
• W2125096269 created "2016-06-24" @default.
• W2125096269 creator A5012208324 @default.
• W2125096269 creator A5022877931 @default.
• W2125096269 creator A5043418752 @default.
• W2125096269 creator A5050160466 @default.
• W2125096269 creator A5052296933 @default.
• W2125096269 creator A5067841141 @default.
• W2125096269 creator A5068805320 @default.
• W2125096269 creator A5076792895 @default.
• W2125096269 creator A5082548129 @default.
• W2125096269 date "2011-07-01" @default.
• W2125096269 modified "2023-10-17" @default.
• W2125096269 title "Horizontal Transfer of the OXA-24 Carbapenemase Gene via Outer Membrane Vesicles: a New Mechanism of Dissemination of Carbapenem Resistance Genes in Acinetobacter baumannii" @default.
• W2125096269 cites W1756755992 @default.
• W2125096269 cites W1822354764 @default.
• W2125096269 cites W1830474721 @default.
• W2125096269 cites W1947936921 @default.
• W2125096269 cites W1971302468 @default.
• W2125096269 cites W1997969528 @default.
• W2125096269 cites W2014368385 @default.
• W2125096269 cites W2015313456 @default.
• W2125096269 cites W2019615869 @default.
• W2125096269 cites W2036999399 @default.
• W2125096269 cites W2041107203 @default.
• W2125096269 cites W2100141503 @default.
• W2125096269 cites W2110313414 @default.
• W2125096269 cites W2115765556 @default.
• W2125096269 cites W2120183465 @default.
• W2125096269 cites W2120556801 @default.
• W2125096269 cites W2124395184 @default.
• W2125096269 cites W2125983377 @default.
• W2125096269 cites W2131481346 @default.
• W2125096269 cites W2136723907 @default.
• W2125096269 cites W2140371210 @default.
• W2125096269 cites W2151446857 @default.
• W2125096269 cites W2151603653 @default.
• W2125096269 cites W2159435953 @default.
• W2125096269 cites W2163623511 @default.
• W2125096269 cites W2169499475 @default.
• W2125096269 cites W2171348592 @default.
• W2125096269 cites W4293247451 @default.
• W2125096269 doi "https://doi.org/10.1128/aac.00929-10" @default.
• W2125096269 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3122458" @default.
• W2125096269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21518847" @default.
• W2125096269 hasPublicationYear "2011" @default.
• W2125096269 type Work @default.
• W2125096269 sameAs 2125096269 @default.
• W2125096269 citedByCount "264" @default.
• W2125096269 countsByYear W21250962692012 @default.
• W2125096269 countsByYear W21250962692013 @default.
• W2125096269 countsByYear W21250962692014 @default.
• W2125096269 countsByYear W21250962692015 @default.
• W2125096269 countsByYear W21250962692016 @default.
• W2125096269 countsByYear W21250962692017 @default.
• W2125096269 countsByYear W21250962692018 @default.
• W2125096269 countsByYear W21250962692019 @default.
• W2125096269 countsByYear W21250962692020 @default.
• W2125096269 countsByYear W21250962692021 @default.
• W2125096269 countsByYear W21250962692022 @default.
• W2125096269 countsByYear W21250962692023 @default.
• W2125096269 crossrefType "journal-article" @default.
• W2125096269 hasAuthorship W2125096269A5012208324 @default.
• W2125096269 hasAuthorship W2125096269A5022877931 @default.
• W2125096269 hasAuthorship W2125096269A5043418752 @default.
• W2125096269 hasAuthorship W2125096269A5050160466 @default.
• W2125096269 hasAuthorship W2125096269A5052296933 @default.
• W2125096269 hasAuthorship W2125096269A5067841141 @default.
• W2125096269 hasAuthorship W2125096269A5068805320 @default.
• W2125096269 hasAuthorship W2125096269A5076792895 @default.
• W2125096269 hasAuthorship W2125096269A5082548129 @default.
• W2125096269 hasBestOaLocation W21250962692 @default.
• W2125096269 hasConcept C104317684 @default.
• W2125096269 hasConcept C146587185 @default.
• W2125096269 hasConcept C22744801 @default.
• W2125096269 hasConcept C2776315533 @default.
• W2125096269 hasConcept C2776685102 @default.
• W2125096269 hasConcept C2777637488 @default.
• W2125096269 hasConcept C501593827 @default.
• W2125096269 hasConcept C523546767 @default.
• W2125096269 hasConcept C54355233 @default.
• W2125096269 hasConcept C547475151 @default.
• W2125096269 hasConcept C86803240 @default.
• W2125096269 hasConcept C89423630 @default.
• W2125096269 hasConcept C90132467 @default.
• W2125096269 hasConcept C92938381 @default.
• W2125096269 hasConceptScore W2125096269C104317684 @default.
• W2125096269 hasConceptScore W2125096269C146587185 @default.
• W2125096269 hasConceptScore W2125096269C22744801 @default.
• W2125096269 hasConceptScore W2125096269C2776315533 @default.
• W2125096269 hasConceptScore W2125096269C2776685102 @default.
• W2125096269 hasConceptScore W2125096269C2777637488 @default.
• W2125096269 hasConceptScore W2125096269C501593827 @default.
• W2125096269 hasConceptScore W2125096269C523546767 @default.
• W2125096269 hasConceptScore W2125096269C54355233 @default.
• W2125096269 hasConceptScore W2125096269C547475151 @default.
• W2125096269 hasConceptScore W2125096269C86803240 @default.
• W2125096269 hasConceptScore W2125096269C89423630 @default.

• next