FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125148969> ?p ?o ?g. }

• W2125148969 endingPage "151" @default.
• W2125148969 startingPage "143" @default.
• W2125148969 abstract "Background Bioluminescence imaging (BLI) is an ideal tool for noninvasive, quantitative monitoring of tumor progression/regression in animal models. The effectiveness of different treatment strategies is displayed by an altered intensity of bioluminescence, demonstrating a change of the tumor burden. The aim of this study was to establish a reliable, reproducible colorectal hepatic metastases cancer animal model. Methods Cells of the human colon carcinoma cell line HCT-116 Lucpos expressing the firefly luciferase enzyme gene were used. HCT-116 Lucpos cells (2.5 × 106) were injected through the portal vein into the liver of immunoincompetent nude mice. BLI was used to analyze intrahepatic tumor burden and growth kinetic. Results HCT-116 Lucpos cells demonstrated a progressive and reproducible growth in the liver after intraportal injection. Four days after injection, the animals were analyzed for tumor growth by BLI, and mice without or too low bioluminescence signals were excluded (between 10% and 20% animals). HCT-116 Lucpos intrahepatic tumors responded successfully to different dosages (5 and 10 mg/kg) of 5-fluorouracil. Conclusions BLI is an important tool with many potential advantages for investigators. The measurement of intrahepatic tumor growth by imaging luciferase activity noninvasively provides valuable information on tumor burden and effectiveness of therapy. Thus, the presented intrahepatic metastases model based on the growth of HCT-116 Lucpos cells is suitable for in vivo testing of different cancer therapy strategies." @default.
• W2125148969 created "2016-06-24" @default.
• W2125148969 creator A5006396543 @default.
• W2125148969 creator A5013927043 @default.
• W2125148969 creator A5016167769 @default.
• W2125148969 creator A5029425659 @default.
• W2125148969 creator A5037455401 @default.
• W2125148969 creator A5046610786 @default.
• W2125148969 creator A5052785511 @default.
• W2125148969 creator A5063988665 @default.
• W2125148969 creator A5067014510 @default.
• W2125148969 creator A5069434242 @default.
• W2125148969 creator A5076169179 @default.
• W2125148969 creator A5080071989 @default.
• W2125148969 date "2013-11-01" @default.
• W2125148969 modified "2023-09-29" @default.
• W2125148969 title "Noninvasive visualization of tumor growth in a human colorectal liver metastases xenograft model using bioluminescence in vivo imaging" @default.
• W2125148969 cites W1518520618 @default.
• W2125148969 cites W1964907928 @default.
• W2125148969 cites W1969616058 @default.
• W2125148969 cites W1975108860 @default.
• W2125148969 cites W1979120586 @default.
• W2125148969 cites W1980873645 @default.
• W2125148969 cites W2008125452 @default.
• W2125148969 cites W2018439279 @default.
• W2125148969 cites W2029231546 @default.
• W2125148969 cites W2036640839 @default.
• W2125148969 cites W2037174767 @default.
• W2125148969 cites W2040117720 @default.
• W2125148969 cites W2058491683 @default.
• W2125148969 cites W2059220502 @default.
• W2125148969 cites W2063808038 @default.
• W2125148969 cites W2066088243 @default.
• W2125148969 cites W2070345146 @default.
• W2125148969 cites W2070763522 @default.
• W2125148969 cites W2071895577 @default.
• W2125148969 cites W2075733574 @default.
• W2125148969 cites W2080275318 @default.
• W2125148969 cites W2128692771 @default.
• W2125148969 cites W2134951683 @default.
• W2125148969 cites W2141040794 @default.
• W2125148969 cites W2149611344 @default.
• W2125148969 cites W2154853638 @default.
• W2125148969 cites W2329613741 @default.
• W2125148969 doi "https://doi.org/10.1016/j.jss.2013.03.024" @default.
• W2125148969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23998649" @default.
• W2125148969 hasPublicationYear "2013" @default.
• W2125148969 type Work @default.
• W2125148969 sameAs 2125148969 @default.
• W2125148969 citedByCount "18" @default.
• W2125148969 countsByYear W21251489692013 @default.
• W2125148969 countsByYear W21251489692014 @default.
• W2125148969 countsByYear W21251489692015 @default.
• W2125148969 countsByYear W21251489692016 @default.
• W2125148969 countsByYear W21251489692017 @default.
• W2125148969 countsByYear W21251489692019 @default.
• W2125148969 countsByYear W21251489692020 @default.
• W2125148969 countsByYear W21251489692022 @default.
• W2125148969 countsByYear W21251489692023 @default.
• W2125148969 crossrefType "journal-article" @default.
• W2125148969 hasAuthorship W2125148969A5006396543 @default.
• W2125148969 hasAuthorship W2125148969A5013927043 @default.
• W2125148969 hasAuthorship W2125148969A5016167769 @default.
• W2125148969 hasAuthorship W2125148969A5029425659 @default.
• W2125148969 hasAuthorship W2125148969A5037455401 @default.
• W2125148969 hasAuthorship W2125148969A5046610786 @default.
• W2125148969 hasAuthorship W2125148969A5052785511 @default.
• W2125148969 hasAuthorship W2125148969A5063988665 @default.
• W2125148969 hasAuthorship W2125148969A5067014510 @default.
• W2125148969 hasAuthorship W2125148969A5069434242 @default.
• W2125148969 hasAuthorship W2125148969A5076169179 @default.
• W2125148969 hasAuthorship W2125148969A5080071989 @default.
• W2125148969 hasConcept C111335760 @default.
• W2125148969 hasConcept C121608353 @default.
• W2125148969 hasConcept C126322002 @default.
• W2125148969 hasConcept C142724271 @default.
• W2125148969 hasConcept C150903083 @default.
• W2125148969 hasConcept C161997846 @default.
• W2125148969 hasConcept C18903297 @default.
• W2125148969 hasConcept C207001950 @default.
• W2125148969 hasConcept C2778117688 @default.
• W2125148969 hasConcept C502942594 @default.
• W2125148969 hasConcept C5176359 @default.
• W2125148969 hasConcept C526805850 @default.
• W2125148969 hasConcept C54009773 @default.
• W2125148969 hasConcept C54355233 @default.
• W2125148969 hasConcept C71924100 @default.
• W2125148969 hasConcept C81885089 @default.
• W2125148969 hasConcept C86803240 @default.
• W2125148969 hasConceptScore W2125148969C111335760 @default.
• W2125148969 hasConceptScore W2125148969C121608353 @default.
• W2125148969 hasConceptScore W2125148969C126322002 @default.
• W2125148969 hasConceptScore W2125148969C142724271 @default.
• W2125148969 hasConceptScore W2125148969C150903083 @default.
• W2125148969 hasConceptScore W2125148969C161997846 @default.
• W2125148969 hasConceptScore W2125148969C18903297 @default.
• W2125148969 hasConceptScore W2125148969C207001950 @default.
• W2125148969 hasConceptScore W2125148969C2778117688 @default.

• next