FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125219944> ?p ?o ?g. }

• W2125219944 endingPage "1184" @default.
• W2125219944 startingPage "1174" @default.
• W2125219944 abstract "Semen is the main vector for human immunodeficiency virus (HIV) transmission from men to women. We investigated the influence of cytokines in semen on local HIV burden and activated T cells.Blood and semen were collected from 42 HIV-negative and 38 HIV-positive men. Concentrations of 20 cytokines were measured by Luminex, and frequencies of activated T cells were measured by flow cytometry.Semen contained higher concentrations of proinflammatory (monocyte chemotactic protein-1, interleukin [IL]-8, IL-6, Fractalkine, macrophage inflammatory protein (MIP)-1β, granulocyte macrophage colony-stimulating factor) and adaptive cytokines (IL-7 and IL-15) and higher frequencies of activated T cells compared to blood. Plasma IL-2, eotaxin, MIP-1β, and IL-15 and semen eotaxin and granulocyte colony-stimulating factor (G-CSF) concentrations were associated with T-cell activation. Cytokines in semen were highly coregulated in HIV-negative men; however, this network was disrupted during HIV infection. Several cytokines in semen correlated with HIV shedding (G-CSF, tumor necrosis factor-alpha [TNF-α], interferon-gamma [IFN-γ], IL-10).Higher levels of inflammation and T-cell activation were observed in semen compared with blood. Seminal G-CSF, which influences neutrophil survival, T-cell function, and dendritic cell activation, was associated with T-cell activation and HIV shedding and may be an important target for reducing HIV shedding or risk." @default.
• W2125219944 created "2016-06-24" @default.
• W2125219944 creator A5001133659 @default.
• W2125219944 creator A5005837112 @default.
• W2125219944 creator A5018542045 @default.
• W2125219944 creator A5022117496 @default.
• W2125219944 creator A5023672466 @default.
• W2125219944 creator A5045605464 @default.
• W2125219944 creator A5050528207 @default.
• W2125219944 creator A5054450393 @default.
• W2125219944 creator A5071885441 @default.
• W2125219944 date "2013-11-23" @default.
• W2125219944 modified "2023-10-16" @default.
• W2125219944 title "Distinct Cytokine Patterns in Semen Influence Local HIV Shedding and HIV Target Cell Activation" @default.
• W2125219944 cites W1531840529 @default.
• W2125219944 cites W1756235282 @default.
• W2125219944 cites W1981127449 @default.
• W2125219944 cites W1983466424 @default.
• W2125219944 cites W1987554589 @default.
• W2125219944 cites W1990457924 @default.
• W2125219944 cites W1990614673 @default.
• W2125219944 cites W1999317797 @default.
• W2125219944 cites W2006363849 @default.
• W2125219944 cites W2011977784 @default.
• W2125219944 cites W2016168268 @default.
• W2125219944 cites W2022936787 @default.
• W2125219944 cites W2027970569 @default.
• W2125219944 cites W2028100045 @default.
• W2125219944 cites W2031375858 @default.
• W2125219944 cites W2046208657 @default.
• W2125219944 cites W2050349991 @default.
• W2125219944 cites W2067045743 @default.
• W2125219944 cites W2076120354 @default.
• W2125219944 cites W2088564232 @default.
• W2125219944 cites W2088823615 @default.
• W2125219944 cites W2090092916 @default.
• W2125219944 cites W2093075648 @default.
• W2125219944 cites W2097569605 @default.
• W2125219944 cites W2105369844 @default.
• W2125219944 cites W2118663100 @default.
• W2125219944 cites W2119334940 @default.
• W2125219944 cites W2128906166 @default.
• W2125219944 cites W2140573695 @default.
• W2125219944 cites W2145615591 @default.
• W2125219944 cites W2147303583 @default.
• W2125219944 cites W2149492547 @default.
• W2125219944 cites W2150484278 @default.
• W2125219944 cites W2156117117 @default.
• W2125219944 cites W2156683317 @default.
• W2125219944 cites W2161784528 @default.
• W2125219944 cites W2321533046 @default.
• W2125219944 cites W2325597058 @default.
• W2125219944 cites W2495570340 @default.
• W2125219944 cites W2587681052 @default.
• W2125219944 cites W4237586762 @default.
• W2125219944 doi "https://doi.org/10.1093/infdis/jit649" @default.
• W2125219944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3969547" @default.
• W2125219944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24273175" @default.
• W2125219944 hasPublicationYear "2013" @default.
• W2125219944 type Work @default.
• W2125219944 sameAs 2125219944 @default.
• W2125219944 citedByCount "39" @default.
• W2125219944 countsByYear W21252199442014 @default.
• W2125219944 countsByYear W21252199442015 @default.
• W2125219944 countsByYear W21252199442016 @default.
• W2125219944 countsByYear W21252199442017 @default.
• W2125219944 countsByYear W21252199442018 @default.
• W2125219944 countsByYear W21252199442019 @default.
• W2125219944 countsByYear W21252199442020 @default.
• W2125219944 countsByYear W21252199442021 @default.
• W2125219944 countsByYear W21252199442022 @default.
• W2125219944 countsByYear W21252199442023 @default.
• W2125219944 crossrefType "journal-article" @default.
• W2125219944 hasAuthorship W2125219944A5001133659 @default.
• W2125219944 hasAuthorship W2125219944A5005837112 @default.
• W2125219944 hasAuthorship W2125219944A5018542045 @default.
• W2125219944 hasAuthorship W2125219944A5022117496 @default.
• W2125219944 hasAuthorship W2125219944A5023672466 @default.
• W2125219944 hasAuthorship W2125219944A5045605464 @default.
• W2125219944 hasAuthorship W2125219944A5050528207 @default.
• W2125219944 hasAuthorship W2125219944A5054450393 @default.
• W2125219944 hasAuthorship W2125219944A5071885441 @default.
• W2125219944 hasBestOaLocation W21252199441 @default.
• W2125219944 hasConcept C164027704 @default.
• W2125219944 hasConcept C16685009 @default.
• W2125219944 hasConcept C17991360 @default.
• W2125219944 hasConcept C203014093 @default.
• W2125219944 hasConcept C2776090121 @default.
• W2125219944 hasConcept C2776914184 @default.
• W2125219944 hasConcept C2778093475 @default.
• W2125219944 hasConcept C2778690821 @default.
• W2125219944 hasConcept C2781184567 @default.
• W2125219944 hasConcept C71924100 @default.
• W2125219944 hasConcept C86803240 @default.
• W2125219944 hasConcept C8891405 @default.
• W2125219944 hasConceptScore W2125219944C164027704 @default.
• W2125219944 hasConceptScore W2125219944C16685009 @default.
• W2125219944 hasConceptScore W2125219944C17991360 @default.

• next