Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125280306> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2125280306 endingPage "182" @default.
- W2125280306 startingPage "175" @default.
- W2125280306 abstract "When studying lung mechanics of intubated premature infants, by the passive-deflation technique we noted that in many flow-volume plots the descending limb was curvilinear with a convexity toward the volume axis. By conventional linear analysis lung mechanics of these patients did not change after the administration of terbutaline, but Mead's tangent-chord slope ratio method for quantifying the amount of curvature showed that the shape of the flow-volume plots did change. Because of the limitations of this method, we developed a microcomputer-based, reiterative regression algorithm which optimizes a nonlinear function for the best fit to any given set of data. We then studied six very low birth weight infants with clinical evidence of pulmonary gas trapping (weight at study, 1.22 +/- 0.29 kg; age, 26 +/- 16 days). We measured respiratory system resistance (Rrs), compliance (Crs), and expiratory time constants (TCrs) by the passive deflation technique before and after subcutaneous administration of 0.02 mg/kg of terbutaline. No effect of terbutaline in a dose sufficient to increase heart rate > 25 beats/min was observed. The same data analyzed using the nonlinear regression technique with a function based upon a two compartment model of parallel inhomogeneities revealed one compartment with relatively normal Rrs, Crs, and TCrs values, and a second compartment with a very high Rrs. The latter fell by 50% after terbutaline. These data suggest that abnormalities of airway resistance in ventilated preterm infants are not easily identifiable by classic linear analysis of lung mechanics.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2125280306 created "2016-06-24" @default.
- W2125280306 creator A5029845794 @default.
- W2125280306 creator A5040502547 @default.
- W2125280306 creator A5048775156 @default.
- W2125280306 creator A5087189828 @default.
- W2125280306 date "1993-03-01" @default.
- W2125280306 modified "2023-09-26" @default.
- W2125280306 title "A nonlinear regression analysis of nonlinear, passive-deflation flow-volume plots" @default.
- W2125280306 cites W1536137827 @default.
- W2125280306 cites W1963384325 @default.
- W2125280306 cites W1967607399 @default.
- W2125280306 cites W1972895696 @default.
- W2125280306 cites W1984793397 @default.
- W2125280306 cites W2035918008 @default.
- W2125280306 cites W2043050097 @default.
- W2125280306 cites W2052708982 @default.
- W2125280306 cites W2058206926 @default.
- W2125280306 cites W2092614853 @default.
- W2125280306 cites W2094588929 @default.
- W2125280306 cites W2116027242 @default.
- W2125280306 cites W2116219344 @default.
- W2125280306 cites W2252935822 @default.
- W2125280306 cites W2267296377 @default.
- W2125280306 cites W2273437865 @default.
- W2125280306 cites W2416879970 @default.
- W2125280306 cites W2442188521 @default.
- W2125280306 cites W2462020450 @default.
- W2125280306 doi "https://doi.org/10.1002/ppul.1950150309" @default.
- W2125280306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8327281" @default.
- W2125280306 hasPublicationYear "1993" @default.
- W2125280306 type Work @default.
- W2125280306 sameAs 2125280306 @default.
- W2125280306 citedByCount "18" @default.
- W2125280306 countsByYear W21252803062012 @default.
- W2125280306 countsByYear W21252803062014 @default.
- W2125280306 countsByYear W21252803062016 @default.
- W2125280306 countsByYear W21252803062017 @default.
- W2125280306 countsByYear W21252803062018 @default.
- W2125280306 countsByYear W21252803062019 @default.
- W2125280306 countsByYear W21252803062020 @default.
- W2125280306 countsByYear W21252803062022 @default.
- W2125280306 countsByYear W21252803062023 @default.
- W2125280306 crossrefType "journal-article" @default.
- W2125280306 hasAuthorship W2125280306A5029845794 @default.
- W2125280306 hasAuthorship W2125280306A5040502547 @default.
- W2125280306 hasAuthorship W2125280306A5048775156 @default.
- W2125280306 hasAuthorship W2125280306A5087189828 @default.
- W2125280306 hasConcept C105922876 @default.
- W2125280306 hasConcept C126322002 @default.
- W2125280306 hasConcept C163498912 @default.
- W2125280306 hasConcept C2776042228 @default.
- W2125280306 hasConcept C2777257755 @default.
- W2125280306 hasConcept C2777714996 @default.
- W2125280306 hasConcept C2780252434 @default.
- W2125280306 hasConcept C33362165 @default.
- W2125280306 hasConcept C33923547 @default.
- W2125280306 hasConcept C42219234 @default.
- W2125280306 hasConcept C534529494 @default.
- W2125280306 hasConcept C71924100 @default.
- W2125280306 hasConceptScore W2125280306C105922876 @default.
- W2125280306 hasConceptScore W2125280306C126322002 @default.
- W2125280306 hasConceptScore W2125280306C163498912 @default.
- W2125280306 hasConceptScore W2125280306C2776042228 @default.
- W2125280306 hasConceptScore W2125280306C2777257755 @default.
- W2125280306 hasConceptScore W2125280306C2777714996 @default.
- W2125280306 hasConceptScore W2125280306C2780252434 @default.
- W2125280306 hasConceptScore W2125280306C33362165 @default.
- W2125280306 hasConceptScore W2125280306C33923547 @default.
- W2125280306 hasConceptScore W2125280306C42219234 @default.
- W2125280306 hasConceptScore W2125280306C534529494 @default.
- W2125280306 hasConceptScore W2125280306C71924100 @default.
- W2125280306 hasIssue "3" @default.
- W2125280306 hasLocation W21252803061 @default.
- W2125280306 hasLocation W21252803062 @default.
- W2125280306 hasOpenAccess W2125280306 @default.
- W2125280306 hasPrimaryLocation W21252803061 @default.
- W2125280306 hasRelatedWork W1589115424 @default.
- W2125280306 hasRelatedWork W1998608300 @default.
- W2125280306 hasRelatedWork W1998824404 @default.
- W2125280306 hasRelatedWork W2039898346 @default.
- W2125280306 hasRelatedWork W2132600855 @default.
- W2125280306 hasRelatedWork W2228496000 @default.
- W2125280306 hasRelatedWork W2321655785 @default.
- W2125280306 hasRelatedWork W2444153312 @default.
- W2125280306 hasRelatedWork W3017204131 @default.
- W2125280306 hasRelatedWork W3130388285 @default.
- W2125280306 hasVolume "15" @default.
- W2125280306 isParatext "false" @default.
- W2125280306 isRetracted "false" @default.
- W2125280306 magId "2125280306" @default.
- W2125280306 workType "article" @default.