Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125331380> ?p ?o ?g. }
- W2125331380 endingPage "2117" @default.
- W2125331380 startingPage "2112" @default.
- W2125331380 abstract "Differentiation of spermatids into spermatozoa is regulated via phosphorylated RNA-binding proteins that modulate the expression of stage-specific mRNAs. We demonstrate that the phosphoserine, -threonine or -tyrosine, interaction protein, Styx, complexes with a testicular RNA-binding protein and is essential for normal spermiogenesis. Ablation of Styx expression in mouse disrupts round and elongating spermatid development, resulting in a >1,000-fold decrease in spermatozoa production. Moreover, Styx −/− males are infertile because of structural head abnormalities in residual epididymal sperm. Immunoprecipitation of Styx with Crhsp-24, a phosphorylated RNA-binding protein implicated in translational repression of histone mRNAs, provides a strategy for regulating posttranscriptional gene expression." @default.
- W2125331380 created "2016-06-24" @default.
- W2125331380 creator A5032372835 @default.
- W2125331380 creator A5043973416 @default.
- W2125331380 date "2002-02-12" @default.
- W2125331380 modified "2023-09-25" @default.
- W2125331380 title "The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production" @default.
- W2125331380 cites W1481335520 @default.
- W2125331380 cites W1558737283 @default.
- W2125331380 cites W1566906383 @default.
- W2125331380 cites W1617092022 @default.
- W2125331380 cites W1966697925 @default.
- W2125331380 cites W1972914977 @default.
- W2125331380 cites W1973309638 @default.
- W2125331380 cites W1984193862 @default.
- W2125331380 cites W1991136563 @default.
- W2125331380 cites W2000149489 @default.
- W2125331380 cites W2020912173 @default.
- W2125331380 cites W2027097889 @default.
- W2125331380 cites W2029276689 @default.
- W2125331380 cites W2029798038 @default.
- W2125331380 cites W2031665308 @default.
- W2125331380 cites W2042629507 @default.
- W2125331380 cites W2043590440 @default.
- W2125331380 cites W2043855098 @default.
- W2125331380 cites W2046275054 @default.
- W2125331380 cites W2047235280 @default.
- W2125331380 cites W2060286193 @default.
- W2125331380 cites W2067346865 @default.
- W2125331380 cites W2073122824 @default.
- W2125331380 cites W2075977131 @default.
- W2125331380 cites W2076983324 @default.
- W2125331380 cites W2079775036 @default.
- W2125331380 cites W2085581069 @default.
- W2125331380 cites W20955563 @default.
- W2125331380 cites W2107532817 @default.
- W2125331380 cites W2107766793 @default.
- W2125331380 cites W2112980613 @default.
- W2125331380 cites W2151371344 @default.
- W2125331380 cites W2164627733 @default.
- W2125331380 cites W2198062791 @default.
- W2125331380 cites W2494477556 @default.
- W2125331380 doi "https://doi.org/10.1073/pnas.251686198" @default.
- W2125331380 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/122327" @default.
- W2125331380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11842224" @default.
- W2125331380 hasPublicationYear "2002" @default.
- W2125331380 type Work @default.
- W2125331380 sameAs 2125331380 @default.
- W2125331380 citedByCount "68" @default.
- W2125331380 countsByYear W21253313802012 @default.
- W2125331380 countsByYear W21253313802013 @default.
- W2125331380 countsByYear W21253313802014 @default.
- W2125331380 countsByYear W21253313802017 @default.
- W2125331380 countsByYear W21253313802019 @default.
- W2125331380 countsByYear W21253313802020 @default.
- W2125331380 countsByYear W21253313802021 @default.
- W2125331380 countsByYear W21253313802022 @default.
- W2125331380 countsByYear W21253313802023 @default.
- W2125331380 crossrefType "journal-article" @default.
- W2125331380 hasAuthorship W2125331380A5032372835 @default.
- W2125331380 hasAuthorship W2125331380A5043973416 @default.
- W2125331380 hasBestOaLocation W21253313802 @default.
- W2125331380 hasConcept C104317684 @default.
- W2125331380 hasConcept C105580179 @default.
- W2125331380 hasConcept C11960822 @default.
- W2125331380 hasConcept C123765429 @default.
- W2125331380 hasConcept C134018914 @default.
- W2125331380 hasConcept C150194340 @default.
- W2125331380 hasConcept C153911025 @default.
- W2125331380 hasConcept C2777394357 @default.
- W2125331380 hasConcept C2778619154 @default.
- W2125331380 hasConcept C2780723820 @default.
- W2125331380 hasConcept C2781087480 @default.
- W2125331380 hasConcept C41282012 @default.
- W2125331380 hasConcept C54355233 @default.
- W2125331380 hasConcept C67705224 @default.
- W2125331380 hasConcept C71829478 @default.
- W2125331380 hasConcept C86803240 @default.
- W2125331380 hasConcept C95444343 @default.
- W2125331380 hasConceptScore W2125331380C104317684 @default.
- W2125331380 hasConceptScore W2125331380C105580179 @default.
- W2125331380 hasConceptScore W2125331380C11960822 @default.
- W2125331380 hasConceptScore W2125331380C123765429 @default.
- W2125331380 hasConceptScore W2125331380C134018914 @default.
- W2125331380 hasConceptScore W2125331380C150194340 @default.
- W2125331380 hasConceptScore W2125331380C153911025 @default.
- W2125331380 hasConceptScore W2125331380C2777394357 @default.
- W2125331380 hasConceptScore W2125331380C2778619154 @default.
- W2125331380 hasConceptScore W2125331380C2780723820 @default.
- W2125331380 hasConceptScore W2125331380C2781087480 @default.
- W2125331380 hasConceptScore W2125331380C41282012 @default.
- W2125331380 hasConceptScore W2125331380C54355233 @default.
- W2125331380 hasConceptScore W2125331380C67705224 @default.
- W2125331380 hasConceptScore W2125331380C71829478 @default.
- W2125331380 hasConceptScore W2125331380C86803240 @default.
- W2125331380 hasConceptScore W2125331380C95444343 @default.
- W2125331380 hasIssue "4" @default.
- W2125331380 hasLocation W21253313801 @default.