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• W2125404363 abstract "Although epidemiologic studies, animal experiments and receptor studies have shown that not only normal ovaries but also many malignant ovarian tumors can be considered as endocrine related and hormone dependent, the place of hormonal therapy in the management of patients with ovarian cancer remains unsettled. Most trials of hormonal treatment in ovarian cancer have been retrospective, involved only limited numbers of patients, and lacked important patient-related data and information pertaining to tumor characteristics. In addition, a variety of hormonal preparations with different degrees of potency and in different dosages were included in these studies. A literature review shows that response to hormonal therapy even in a preterminal setting, is modest, with about 8% objective response but almost no side effects. In a similar patient setting, more toxic therapeutic agents do not yield a better response. The place of hormonal therapy in the management of patients with epithelial ovarian cancer needs more thorough evaluation in well-designed randomized trials." @default.
• W2125404363 created "2016-06-24" @default.
• W2125404363 creator A5066695331 @default.
• W2125404363 date "2000-06-01" @default.
• W2125404363 modified "2023-09-23" @default.
• W2125404363 title "Hormone therapy in epithelial ovarian cancer." @default.
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• W2125404363 doi "https://doi.org/10.1677/erc.0.0070085" @default.
• W2125404363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10903526" @default.
• W2125404363 hasPublicationYear "2000" @default.
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