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• W2125432992 abstract "This study was conducted to evaluate the protective effects of organic and sulfur treated apricot on the azoxymethane-induced carcinogenesis by antioxidant markers and telomerase activity. Spraque Dawley rats (n = 35) were fed with  two kinds of  dried apricots (sun-dried or sulfur fumigated), with or without azoxhymethane (AOM). Rats were sacrificed after seven weeks for measurement of reduced  glutathione,  malondialdehyde, nitric oxide levels and  telomerase activity. The results demonstrated that, oxidative stress and telomerase activity were increased in AOM induced group; decreased in apricot fed group (p < 0.001). With respect to the antioxidant activity; sulfur fumigated apricot group could be more effective than the sun-dried apricot (p < 0.005). On the contrary, telomerase activity was found to be higher in AOM induced sulfur fumigated apricot  group compared to that of the group with AOM  and organic apricot. These results demonstrate that sulfur fumigated apricot or sun dried apricot + azoxhymethane groups had higher antioxidant activity compared to azoxhymethane group. Sun-dried apricot decreaseD the telomerase activity more than sulphur fumigated apricot in azoxyhmethane administirated rats. Apricot treatment also decreased oxidative damage. Taken together, reduction in both telomerase activity and oxidative stress might indicate the benefical effects of apricot suplements against the damages caused by azoxhymethane in rats. Key words: Apricot, azoxhymethane, glutathione, malondialdehyde, nitric oxide, telomerase." @default.
• W2125432992 created "2016-06-24" @default.
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• W2125432992 date "2014-11-30" @default.
• W2125432992 modified "2023-10-12" @default.
• W2125432992 title "Comparision between the effects of dietary suplements of sun dried or sulfur fumigated apricots on the telomerase activity and oxidatve stress parameters in azoxymethane administered rats" @default.
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• W2125432992 doi "https://doi.org/10.5897/ijnam2014.0165" @default.
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