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- W2125479173 abstract "SUMMARY We report an objective examination of nosocomial transmission events derived from long-term (10-year) data from a single medical centre. Cluster analysis, based on the temporal proximity of genetically identical isolates of the respiratory pathogen Moraxella catarrhalis , identified 40 transmission events involving 33 of the 52 genotypes represented by multiple isolates. There was no evidence of highly transmissible or outbreak-prone genotypes. Although most clusters were small (mean size 3·6 isolates) and of short duration (median duration 25 days), clustering accounted for 38·7% of all isolates. Significant risk factors for clustering were multi-bed wards, and winter and spring season, but bacterial antibiotic resistance, manifested as the ability to produce a β-lactamase was not a risk factor. The use of cluster analysis to identify transmission events and its application to long-term data demonstrate an approach to pathogen transmission that should find wide application beyond hospital populations." @default.
- W2125479173 created "2016-06-24" @default.
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- W2125479173 date "2008-09-15" @default.
- W2125479173 modified "2023-09-25" @default.
- W2125479173 title "Nosocomial transmission clusters and risk factors inMoraxella catarrhalis" @default.
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- W2125479173 doi "https://doi.org/10.1017/s0950268808001283" @default.
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