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• W2125494139 abstract "SUMMARY Present evidence suggests that reticulo-cortical circuits are important in the elaboration of the generalized spike-wave rhythm in the EEG and the concomitant symptomatology of petit mal seizures. The spike-wave complex is a polyphasic potential having its onset with a small triphasic spike and subsequently, or sometimes solely, a positive transient preceding the classical spike. Unitary recordings show that this surface positivity coincides with a depth negative wave which is associated with spike discharges. It is suggested that summated EPSPs or depolarization shifts, alternating with IPSPs and hyperpolarization shifts, are the intracellular correlates of the initial positivity-spikes and the wave. Probably the majority of cells fire in bursts with the spike 1, positive transient and spike 2 phase of the spike-wave complex of petit mal epilepsy. Some cells however, do not appear to be influenced or may even be inhibited. Cells which are not actively discharging in the spike-wave rhythm may begin to fire during the grand mal type of electrographic seizure. RÉSUMÉ Les résultats rapportés suggèrent que les circuits réticulo-corticaux ont une grande importance dans l'élaboration des rythmes de pointe-ondes généralisées, recueillis en EEG et pour la symptomatologie concomittante des crises de petit mal. Le complexe pointe-onde est un potentiel polyphasique ayant à son début une pointe triphasique de faible amplitude et ultérieurement, et quelquefois uniquement, une phase positive précédant la pointe classique. Des enregistrements unitaires montrent que l'onde surface-positive coincide avec une onde recueillie dans la profondeur surface-négative, qui est associée avec la décharge de pointe. Il est suggéré que les EPSP sommées ou les modifications de dépolarisation, sont les corrélations intracellulaires des pointes positives initiales et de l'onde. Il est probable que la majorité des cellules s'enflamme en bouffées avec la pointe No. 1, la phase positive transitoire et la pointe No. 2 du complexe pointe-onde de l'épilepsie petit mal. Quelques cellules cependant ne semblent pas influencées et au contraire peuvent être inhibées. Les cellules qui ne déchargent pas activement avec le rythme pointe-onde peuvent commencer à s'enflammer pendant la crise électrographique de type grand mal." @default.
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• W2125494139 date "1966-03-01" @default.
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• W2125494139 title "Extracellular Unit Activity in Cat Cortex during the Spike-Wave Complex" @default.
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• W2125494139 doi "https://doi.org/10.1111/j.1528-1157.1966.tb03368.x" @default.
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