Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125508082> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2125508082 endingPage "192" @default.
- W2125508082 startingPage "182" @default.
- W2125508082 abstract "Translational clinical trials are small studies of therapies emerging from the laboratory. These trials are essential for generating early evidence regarding the effects of treatment on specific targets in the disease pathway and for guiding the next studies to be done. The statistical properties of such studies have been neglected, in part, because they do not fit the well-known clinical trials developmental paradigm. This paper discusses the translational trial setting, and presents an information (entropy) based approach to understanding the properties and use of these trials. The combination of biological knowledge with a designed experiment (albeit a small one) is a powerful device for resolving much of the considerable uncertainty surrounding an emerging therapeutic concept. An approach to motivating the sample size for translational trials is presented." @default.
- W2125508082 created "2016-06-24" @default.
- W2125508082 creator A5087391729 @default.
- W2125508082 date "2005-04-01" @default.
- W2125508082 modified "2023-09-24" @default.
- W2125508082 title "Translational clinical trials: an entropy-based approach to sample size" @default.
- W2125508082 cites W1685767245 @default.
- W2125508082 cites W1965555277 @default.
- W2125508082 cites W1976583576 @default.
- W2125508082 cites W1988262475 @default.
- W2125508082 cites W1995875735 @default.
- W2125508082 cites W2028976744 @default.
- W2125508082 cites W2053565514 @default.
- W2125508082 cites W2060496070 @default.
- W2125508082 cites W2076580309 @default.
- W2125508082 cites W2082449520 @default.
- W2125508082 cites W2106697058 @default.
- W2125508082 cites W2395566801 @default.
- W2125508082 doi "https://doi.org/10.1191/1740774505cn078oa" @default.
- W2125508082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16279140" @default.
- W2125508082 hasPublicationYear "2005" @default.
- W2125508082 type Work @default.
- W2125508082 sameAs 2125508082 @default.
- W2125508082 citedByCount "28" @default.
- W2125508082 countsByYear W21255080822013 @default.
- W2125508082 countsByYear W21255080822015 @default.
- W2125508082 countsByYear W21255080822016 @default.
- W2125508082 countsByYear W21255080822017 @default.
- W2125508082 countsByYear W21255080822018 @default.
- W2125508082 countsByYear W21255080822019 @default.
- W2125508082 countsByYear W21255080822020 @default.
- W2125508082 countsByYear W21255080822021 @default.
- W2125508082 countsByYear W21255080822022 @default.
- W2125508082 countsByYear W21255080822023 @default.
- W2125508082 crossrefType "journal-article" @default.
- W2125508082 hasAuthorship W2125508082A5087391729 @default.
- W2125508082 hasConcept C105795698 @default.
- W2125508082 hasConcept C128544194 @default.
- W2125508082 hasConcept C129848803 @default.
- W2125508082 hasConcept C142724271 @default.
- W2125508082 hasConcept C19527891 @default.
- W2125508082 hasConcept C33923547 @default.
- W2125508082 hasConcept C41008148 @default.
- W2125508082 hasConcept C535046627 @default.
- W2125508082 hasConcept C71924100 @default.
- W2125508082 hasConceptScore W2125508082C105795698 @default.
- W2125508082 hasConceptScore W2125508082C128544194 @default.
- W2125508082 hasConceptScore W2125508082C129848803 @default.
- W2125508082 hasConceptScore W2125508082C142724271 @default.
- W2125508082 hasConceptScore W2125508082C19527891 @default.
- W2125508082 hasConceptScore W2125508082C33923547 @default.
- W2125508082 hasConceptScore W2125508082C41008148 @default.
- W2125508082 hasConceptScore W2125508082C535046627 @default.
- W2125508082 hasConceptScore W2125508082C71924100 @default.
- W2125508082 hasIssue "2" @default.
- W2125508082 hasLocation W21255080821 @default.
- W2125508082 hasLocation W21255080822 @default.
- W2125508082 hasOpenAccess W2125508082 @default.
- W2125508082 hasPrimaryLocation W21255080821 @default.
- W2125508082 hasRelatedWork W2028545055 @default.
- W2125508082 hasRelatedWork W2082770695 @default.
- W2125508082 hasRelatedWork W2125508082 @default.
- W2125508082 hasRelatedWork W2494822104 @default.
- W2125508082 hasRelatedWork W2748952813 @default.
- W2125508082 hasRelatedWork W2888888819 @default.
- W2125508082 hasRelatedWork W2895507049 @default.
- W2125508082 hasRelatedWork W2899084033 @default.
- W2125508082 hasRelatedWork W4327698572 @default.
- W2125508082 hasRelatedWork W4366393762 @default.
- W2125508082 hasVolume "2" @default.
- W2125508082 isParatext "false" @default.
- W2125508082 isRetracted "false" @default.
- W2125508082 magId "2125508082" @default.
- W2125508082 workType "article" @default.