FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125543888> ?p ?o ?g. }

• W2125543888 endingPage "548" @default.
• W2125543888 startingPage "540" @default.
• W2125543888 abstract "A monoclonal antibody (MAb) (MAb 10F3) directed against the CopB outer membrane protein of Moraxella catarrhalis previously was found to enhance pulmonary clearance of M. catarrhalis in an animal model (M. Helminen, I. Maciver, J. L. Latimer, L. D. Cope, G. H. McCracken, Jr., and E. J. Hansen, Infect. Immun. 61:2003-2010, 1993). In the present study, this same MAb was shown to exert complement-dependent bactericidal activity against this pathogen in vitro. Nucleotide sequence analysis of the copB gene from two MAb 10F3-reactive and two MAb 10F3-unreactive strains of M. catarrhalis revealed that the deduced amino acid sequences of these four CopB proteins were at least 90% identical. Comparison of the amino acid sequences of these proteins allowed localization of possible MAb 10F3 binding sites to five relatively small regions of the CopB protein from M. catarrhalis O35E. When five synthetic peptides representing these regions were tested for their ability to bind MAb 10F3 in a direct enzyme-linked immunosorbent assay system, an oligopeptide containing 26 amino acids was shown to bind this MAb. The actual binding region for MAb 10F3 was localized further through the use of overlapping decapeptides that spanned this 26-mer. A fusion protein containing the same 26-mer readily bound MAb 10F3 and was used to immunize mice. The resultant antiserum contained antibodies that reacted with the CopB protein of the homologous M. catarrhalis strain in Western blot analysis and bound to the surface of both homologous and heterologous strains of M. catarrhalis." @default.
• W2125543888 created "2016-06-24" @default.
• W2125543888 creator A5000276109 @default.
• W2125543888 creator A5018439506 @default.
• W2125543888 creator A5032511606 @default.
• W2125543888 creator A5040281068 @default.
• W2125543888 creator A5048556731 @default.
• W2125543888 creator A5082417498 @default.
• W2125543888 creator A5019506360 @default.
• W2125543888 date "1998-02-01" @default.
• W2125543888 modified "2023-10-14" @default.
• W2125543888 title "Mapping of a Protective Epitope of the CopB Outer Membrane Protein of <i>Moraxella catarrhalis</i>" @default.
• W2125543888 cites W1542067597 @default.
• W2125543888 cites W1754607561 @default.
• W2125543888 cites W1838448561 @default.
• W2125543888 cites W1872355798 @default.
• W2125543888 cites W1886381360 @default.
• W2125543888 cites W1889943289 @default.
• W2125543888 cites W1893661547 @default.
• W2125543888 cites W1956506549 @default.
• W2125543888 cites W1964689554 @default.
• W2125543888 cites W1972468891 @default.
• W2125543888 cites W1974053104 @default.
• W2125543888 cites W1975304761 @default.
• W2125543888 cites W1977461031 @default.
• W2125543888 cites W1979040408 @default.
• W2125543888 cites W1985545067 @default.
• W2125543888 cites W1987958450 @default.
• W2125543888 cites W1992969503 @default.
• W2125543888 cites W1993865754 @default.
• W2125543888 cites W2009620784 @default.
• W2125543888 cites W2011372164 @default.
• W2125543888 cites W2017976174 @default.
• W2125543888 cites W2026386282 @default.
• W2125543888 cites W2029713105 @default.
• W2125543888 cites W2030686497 @default.
• W2125543888 cites W2034792616 @default.
• W2125543888 cites W2061457641 @default.
• W2125543888 cites W2062690674 @default.
• W2125543888 cites W2074070121 @default.
• W2125543888 cites W2076237478 @default.
• W2125543888 cites W2077248074 @default.
• W2125543888 cites W2088477916 @default.
• W2125543888 cites W2097339088 @default.
• W2125543888 cites W2103091271 @default.
• W2125543888 cites W2107068916 @default.
• W2125543888 cites W2109249415 @default.
• W2125543888 cites W2112795143 @default.
• W2125543888 cites W2127998202 @default.
• W2125543888 cites W2134261057 @default.
• W2125543888 cites W2155879746 @default.
• W2125543888 cites W2159905974 @default.
• W2125543888 cites W2163221018 @default.
• W2125543888 cites W2166695910 @default.
• W2125543888 cites W2168384204 @default.
• W2125543888 cites W2319108114 @default.
• W2125543888 cites W2330072357 @default.
• W2125543888 cites W3143362498 @default.
• W2125543888 cites W4240276000 @default.
• W2125543888 cites W4241170897 @default.
• W2125543888 cites W4254692869 @default.
• W2125543888 doi "https://doi.org/10.1128/iai.66.2.540-548.1998" @default.
• W2125543888 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/107939" @default.
• W2125543888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9453607" @default.
• W2125543888 hasPublicationYear "1998" @default.
• W2125543888 type Work @default.
• W2125543888 sameAs 2125543888 @default.
• W2125543888 citedByCount "45" @default.
• W2125543888 countsByYear W21255438882012 @default.
• W2125543888 countsByYear W21255438882013 @default.
• W2125543888 countsByYear W21255438882016 @default.
• W2125543888 countsByYear W21255438882017 @default.
• W2125543888 countsByYear W21255438882020 @default.
• W2125543888 crossrefType "journal-article" @default.
• W2125543888 hasAuthorship W2125543888A5000276109 @default.
• W2125543888 hasAuthorship W2125543888A5018439506 @default.
• W2125543888 hasAuthorship W2125543888A5019506360 @default.
• W2125543888 hasAuthorship W2125543888A5032511606 @default.
• W2125543888 hasAuthorship W2125543888A5040281068 @default.
• W2125543888 hasAuthorship W2125543888A5048556731 @default.
• W2125543888 hasAuthorship W2125543888A5082417498 @default.
• W2125543888 hasBestOaLocation W21255438881 @default.
• W2125543888 hasConcept C104317684 @default.
• W2125543888 hasConcept C153911025 @default.
• W2125543888 hasConcept C159654299 @default.
• W2125543888 hasConcept C167625842 @default.
• W2125543888 hasConcept C195616568 @default.
• W2125543888 hasConcept C2776551000 @default.
• W2125543888 hasConcept C2776925733 @default.
• W2125543888 hasConcept C2910443534 @default.
• W2125543888 hasConcept C501593827 @default.
• W2125543888 hasConcept C542903549 @default.
• W2125543888 hasConcept C54355233 @default.
• W2125543888 hasConcept C55493867 @default.
• W2125543888 hasConcept C86803240 @default.
• W2125543888 hasConcept C89423630 @default.
• W2125543888 hasConcept C91523082 @default.
• W2125543888 hasConceptScore W2125543888C104317684 @default.

• next