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• W2125575438 abstract "TONSOKU(TSK)/MGOUN3/BRUSHY1 of Arabidopsis thaliana encodes a nuclear leucine-glycine-aspargine (LGN) domain protein implicated to be involved in genome maintenance, and mutants with defects in TSK show a fasciated stem with disorganized meristem structures. We identified a homolog of TSK from tobacco BY-2 cells (NtTSK), which showed high sequence conservation both in the LGN domain and in leucine-rich repeats with AtTSK. The NtTSK gene was expressed during S phase of the cell cycle in tobacco BY-2 cells highly synchronized for cell division. The tsk mutants of Arabidopsis contained an increased proportion of cells with 4C nuclei and cells expressing cyclin B1 compared with the wild type. These results suggest that TSK is required during the cell cycle and defects of TSK cause the arrest of cell cycle progression at G2/M phase." @default.
• W2125575438 created "2016-06-24" @default.
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• W2125575438 date "2005-05-01" @default.
• W2125575438 modified "2023-09-27" @default.
• W2125575438 title "TONSOKU is Expressed in S Phase of the Cell Cycle and its Defect Delays Cell Cycle Progression in Arabidopsis" @default.
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• W2125575438 doi "https://doi.org/10.1093/pcp/pci082" @default.
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