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- W2125582289 abstract "beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles)." @default.
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- W2125582289 date "1983-04-01" @default.
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- W2125582289 title "Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants" @default.
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- W2125582289 doi "https://doi.org/10.1128/aac.23.4.622" @default.
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