Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125629208> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2125629208 endingPage "638" @default.
- W2125629208 startingPage "629" @default.
- W2125629208 abstract "In the one year since isotretinoin has been available in the United States for the treatment of severe, recalcitrant, nodulocystic acne, there has been extensive clinical verification of the reports of its dramatic efficacy in the treatment of this troublesome disease. Proper selection of patients, as well as treatment with adequate doses of drug for 3 to 5 months, will most often result in significant clinical improvement or total clearing. Although dosages of less than 1 mg/kg/day may produce a nearly equivalent degree of improvement with somewhat fewer or less severe side effects, the recommended daily dose remains 1 mg/kg/day because lower dosages are associated with more frequent relapses. In severe cases, the daily dosage may be increased to 2 mg/kg/day. Teratogenicity, elevation of serum triglycerides, liver function abnormalities, pancreatitis, and pseudotumor cerebri may all be associated with isotretinoin therapy and require close monitoring of the patient. In the one year since isotretinoin has been available in the United States for the treatment of severe, recalcitrant, nodulocystic acne, there has been extensive clinical verification of the reports of its dramatic efficacy in the treatment of this troublesome disease. Proper selection of patients, as well as treatment with adequate doses of drug for 3 to 5 months, will most often result in significant clinical improvement or total clearing. Although dosages of less than 1 mg/kg/day may produce a nearly equivalent degree of improvement with somewhat fewer or less severe side effects, the recommended daily dose remains 1 mg/kg/day because lower dosages are associated with more frequent relapses. In severe cases, the daily dosage may be increased to 2 mg/kg/day. Teratogenicity, elevation of serum triglycerides, liver function abnormalities, pancreatitis, and pseudotumor cerebri may all be associated with isotretinoin therapy and require close monitoring of the patient." @default.
- W2125629208 created "2016-06-24" @default.
- W2125629208 creator A5007134281 @default.
- W2125629208 creator A5067757102 @default.
- W2125629208 creator A5072950389 @default.
- W2125629208 creator A5073902530 @default.
- W2125629208 creator A5084529068 @default.
- W2125629208 date "1983-10-01" @default.
- W2125629208 modified "2023-09-29" @default.
- W2125629208 title "Isotretinoin treatment of acne and related disorders: An update" @default.
- W2125629208 cites W1584295824 @default.
- W2125629208 cites W1973340566 @default.
- W2125629208 cites W2007858816 @default.
- W2125629208 cites W2015824214 @default.
- W2125629208 cites W2025228940 @default.
- W2125629208 cites W2049647488 @default.
- W2125629208 cites W2071398502 @default.
- W2125629208 cites W2145046666 @default.
- W2125629208 doi "https://doi.org/10.1016/s0190-9622(83)70176-3" @default.
- W2125629208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6226726" @default.
- W2125629208 hasPublicationYear "1983" @default.
- W2125629208 type Work @default.
- W2125629208 sameAs 2125629208 @default.
- W2125629208 citedByCount "123" @default.
- W2125629208 countsByYear W21256292082012 @default.
- W2125629208 countsByYear W21256292082013 @default.
- W2125629208 countsByYear W21256292082014 @default.
- W2125629208 countsByYear W21256292082015 @default.
- W2125629208 countsByYear W21256292082016 @default.
- W2125629208 countsByYear W21256292082017 @default.
- W2125629208 countsByYear W21256292082018 @default.
- W2125629208 countsByYear W21256292082019 @default.
- W2125629208 countsByYear W21256292082020 @default.
- W2125629208 countsByYear W21256292082021 @default.
- W2125629208 crossrefType "journal-article" @default.
- W2125629208 hasAuthorship W2125629208A5007134281 @default.
- W2125629208 hasAuthorship W2125629208A5067757102 @default.
- W2125629208 hasAuthorship W2125629208A5072950389 @default.
- W2125629208 hasAuthorship W2125629208A5073902530 @default.
- W2125629208 hasAuthorship W2125629208A5084529068 @default.
- W2125629208 hasConcept C126322002 @default.
- W2125629208 hasConcept C141071460 @default.
- W2125629208 hasConcept C16005928 @default.
- W2125629208 hasConcept C162156334 @default.
- W2125629208 hasConcept C2776285725 @default.
- W2125629208 hasConcept C2777288759 @default.
- W2125629208 hasConcept C2777673923 @default.
- W2125629208 hasConcept C71924100 @default.
- W2125629208 hasConceptScore W2125629208C126322002 @default.
- W2125629208 hasConceptScore W2125629208C141071460 @default.
- W2125629208 hasConceptScore W2125629208C16005928 @default.
- W2125629208 hasConceptScore W2125629208C162156334 @default.
- W2125629208 hasConceptScore W2125629208C2776285725 @default.
- W2125629208 hasConceptScore W2125629208C2777288759 @default.
- W2125629208 hasConceptScore W2125629208C2777673923 @default.
- W2125629208 hasConceptScore W2125629208C71924100 @default.
- W2125629208 hasIssue "4" @default.
- W2125629208 hasLocation W21256292081 @default.
- W2125629208 hasLocation W21256292082 @default.
- W2125629208 hasOpenAccess W2125629208 @default.
- W2125629208 hasPrimaryLocation W21256292081 @default.
- W2125629208 hasRelatedWork W1831466767 @default.
- W2125629208 hasRelatedWork W2027614408 @default.
- W2125629208 hasRelatedWork W2091461711 @default.
- W2125629208 hasRelatedWork W2305922381 @default.
- W2125629208 hasRelatedWork W2563438566 @default.
- W2125629208 hasRelatedWork W2572390839 @default.
- W2125629208 hasRelatedWork W2789590115 @default.
- W2125629208 hasRelatedWork W2791757255 @default.
- W2125629208 hasRelatedWork W2991560005 @default.
- W2125629208 hasRelatedWork W4385231871 @default.
- W2125629208 hasVolume "9" @default.
- W2125629208 isParatext "false" @default.
- W2125629208 isRetracted "false" @default.
- W2125629208 magId "2125629208" @default.
- W2125629208 workType "article" @default.