FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125657777> ?p ?o ?g. }

• W2125657777 endingPage "513" @default.
• W2125657777 startingPage "505" @default.
• W2125657777 abstract "1 Using the conventional whole-cell clamp method, the electrical responses of individual smooth muscle and endothelial cells to acetylcholine (ACh) were observed in multicellular preparations where the two types of cells remained in close apposition. 2 In both types of cells, ACh induced similar hyperpolarizing responses which, when recorded in current clamp mode, had two phases (an initial fast and a second slower phase). 3 After blocking gap junctions, including myoendothelial junctions, with 18β-glycyrrhetinic acid, ACh induced an outward current with two phases in voltage-clamped endothelial cells. The outward current appeared around −90 mV and increased linearly with the membrane depolarization. 4 In smooth muscle cells, ACh failed to induce a membrane current after gap junctions had been blocked with 18β-glycyrrhetinic acid. The inhibition of ACh-induced response by 18β-glycyrrhetinic acid was observed using either sharp or patch electrodes. 5 Nominally Ca2+-free solution reduced the initial phase and abolished the second phase of ACh-induced responses of endothelial cells. Both phases were also reduced by charybdotoxin (CTX). 6 Our results indicate that in guinea-pig mesenteric arterioles, ACh hyperpolarizes endothelial cells by activating Ca2+-activated K+ channels which are sensitive to CTX. On the other hand, hyperpolarizing responses detected in smooth muscle cells seem to originate in endothelial cells and conduct to the muscle layer via myoendothelial gap junctions." @default.
• W2125657777 created "2016-06-24" @default.
• W2125657777 creator A5026151137 @default.
• W2125657777 creator A5046362015 @default.
• W2125657777 creator A5057699300 @default.
• W2125657777 date "1999-01-01" @default.
• W2125657777 modified "2023-10-10" @default.
• W2125657777 title "Endothelium‐dependent hyperpolarization and intercellular electrical coupling in guinea‐pig mesenteric arterioles" @default.
• W2125657777 cites W108816817 @default.
• W2125657777 cites W1804324016 @default.
• W2125657777 cites W1967368698 @default.
• W2125657777 cites W1988160513 @default.
• W2125657777 cites W1994931711 @default.
• W2125657777 cites W2001287424 @default.
• W2125657777 cites W2005284425 @default.
• W2125657777 cites W2010763573 @default.
• W2125657777 cites W2012185701 @default.
• W2125657777 cites W2015095580 @default.
• W2125657777 cites W2027504703 @default.
• W2125657777 cites W2027662236 @default.
• W2125657777 cites W2028028524 @default.
• W2125657777 cites W2040425611 @default.
• W2125657777 cites W2041049233 @default.
• W2125657777 cites W2044759304 @default.
• W2125657777 cites W2044930326 @default.
• W2125657777 cites W2073924708 @default.
• W2125657777 cites W2076783344 @default.
• W2125657777 cites W2087873957 @default.
• W2125657777 cites W2104308614 @default.
• W2125657777 cites W2125742651 @default.
• W2125657777 cites W2129304805 @default.
• W2125657777 cites W2138046394 @default.
• W2125657777 cites W2144486173 @default.
• W2125657777 cites W2256783719 @default.
• W2125657777 cites W2419001153 @default.
• W2125657777 cites W75632855 @default.
• W2125657777 doi "https://doi.org/10.1111/j.1469-7793.1999.505ae.x" @default.
• W2125657777 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2269064" @default.
• W2125657777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9852331" @default.
• W2125657777 hasPublicationYear "1999" @default.
• W2125657777 type Work @default.
• W2125657777 sameAs 2125657777 @default.
• W2125657777 citedByCount "182" @default.
• W2125657777 countsByYear W21256577772012 @default.
• W2125657777 countsByYear W21256577772013 @default.
• W2125657777 countsByYear W21256577772014 @default.
• W2125657777 countsByYear W21256577772015 @default.
• W2125657777 countsByYear W21256577772016 @default.
• W2125657777 countsByYear W21256577772017 @default.
• W2125657777 countsByYear W21256577772018 @default.
• W2125657777 countsByYear W21256577772019 @default.
• W2125657777 countsByYear W21256577772020 @default.
• W2125657777 countsByYear W21256577772021 @default.
• W2125657777 countsByYear W21256577772022 @default.
• W2125657777 countsByYear W21256577772023 @default.
• W2125657777 crossrefType "journal-article" @default.
• W2125657777 hasAuthorship W2125657777A5026151137 @default.
• W2125657777 hasAuthorship W2125657777A5046362015 @default.
• W2125657777 hasAuthorship W2125657777A5057699300 @default.
• W2125657777 hasBestOaLocation W21256577772 @default.
• W2125657777 hasConcept C100837961 @default.
• W2125657777 hasConcept C12554922 @default.
• W2125657777 hasConcept C131453863 @default.
• W2125657777 hasConcept C134018914 @default.
• W2125657777 hasConcept C147944092 @default.
• W2125657777 hasConcept C1491633281 @default.
• W2125657777 hasConcept C158157758 @default.
• W2125657777 hasConcept C169760540 @default.
• W2125657777 hasConcept C178790620 @default.
• W2125657777 hasConcept C181911157 @default.
• W2125657777 hasConcept C185263204 @default.
• W2125657777 hasConcept C185592680 @default.
• W2125657777 hasConcept C2775910092 @default.
• W2125657777 hasConcept C2777151030 @default.
• W2125657777 hasConcept C2780419564 @default.
• W2125657777 hasConcept C29350253 @default.
• W2125657777 hasConcept C4141045 @default.
• W2125657777 hasConcept C55493867 @default.
• W2125657777 hasConcept C66974803 @default.
• W2125657777 hasConcept C79879829 @default.
• W2125657777 hasConcept C86803240 @default.
• W2125657777 hasConcept C95444343 @default.
• W2125657777 hasConceptScore W2125657777C100837961 @default.
• W2125657777 hasConceptScore W2125657777C12554922 @default.
• W2125657777 hasConceptScore W2125657777C131453863 @default.
• W2125657777 hasConceptScore W2125657777C134018914 @default.
• W2125657777 hasConceptScore W2125657777C147944092 @default.
• W2125657777 hasConceptScore W2125657777C1491633281 @default.
• W2125657777 hasConceptScore W2125657777C158157758 @default.
• W2125657777 hasConceptScore W2125657777C169760540 @default.
• W2125657777 hasConceptScore W2125657777C178790620 @default.
• W2125657777 hasConceptScore W2125657777C181911157 @default.
• W2125657777 hasConceptScore W2125657777C185263204 @default.
• W2125657777 hasConceptScore W2125657777C185592680 @default.
• W2125657777 hasConceptScore W2125657777C2775910092 @default.
• W2125657777 hasConceptScore W2125657777C2777151030 @default.
• W2125657777 hasConceptScore W2125657777C2780419564 @default.
• W2125657777 hasConceptScore W2125657777C29350253 @default.

• next