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- W2125792276 abstract "<h3>Hypothesis</h3> Primary anastomosis following intestinal resection is a valid surgical option in the treatment of infants with necrotizing enterocolitis (NEC) who weigh less than 1000 g. <h3>Design</h3> Retrospective case series. <h3>Setting</h3> Tertiary neonatal surgery referral center. <h3>Patients</h3> All infants with confirmed NEC weighing less than 1000 g admitted to our intensive care unit over 4 years. <h3>Intervention</h3> For infants requiring laparotomy and intestinal resection, primary anastomosis was performed whenever the clinical condition permitted. <h3>Main Outcome Measures</h3> Short- and long-term survival, length of intensive care unit stay, and complications. <h3>Results</h3> Fifty-one infants with NEC who weighed less than 1000 g were admitted during the study period. Twelve infants underwent intestinal resection and primary anastomosis (median weight at surgery, 0.83 kg; range, 0.6-0.96 kg). One infant developed recurrent NEC, requiring further surgery, but there were no anastomotic leakages and no strictures. The median postoperative stay on our intensive care unit was 14 days (range, 2-49 days). All 12 infants survived their episode of acute NEC, and 8 are alive, with a median follow-up of 34.2 months (range, 4.7-48.4 months). Only 1 death was related to NEC. During the same period, 14 infants underwent intestinal resection and stoma formation. Ten survived the acute episode, and 6 are alive at a median follow-up of 24.0 months (range, 13.1-33.9 months). The median postoperative intensive care unit stay was 18 days (range, 2-74 days). Necrotizing enterocolitis–related complications occurred in 8 of these infants. <h3>Conclusions</h3> The outcome of infants with NEC who weigh less than 1000 g and undergo primary anastomosis is comparable to that of infants treated using alternative techniques. It is, therefore, a valid surgical option in selected infants. The mortality in this group of infants is high." @default.
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- W2125792276 date "2005-12-01" @default.
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- W2125792276 title "Resection and Primary Anastomosis Is a Valid Surgical Option for Infants With Necrotizing Enterocolitis Who Weigh Less Than 1000 g" @default.
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- W2125792276 doi "https://doi.org/10.1001/archsurg.140.12.1149" @default.
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