FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125868049> ?p ?o ?g. }

• W2125868049 endingPage "1159" @default.
• W2125868049 startingPage "1159" @default.
• W2125868049 abstract "Conclusion: In patients with ruptured abdominal aortic aneurysms (AAA) who require massive transfusion, a more equivalent ratio of transfusion of packed red blood cells (PRBC) to fresh frozen plasma (FFP) is independently associated with lower 30-day mortality. Summary: Adverse predictors for survival after ruptured AAA include advanced age, preoperative shock, poor intraoperative hemodynamics, oliguria, and postoperative complications. Improved outcomes are associated with surgeon volume and specialty training. Researchers in resuscitation research have recently focused on types and amounts of blood products administered with respect to mortality after massive hemorrhage from trauma. It appears, that mortality in trauma patients who require at least 10 units of blood products in <24 hours can be decreased with increased administration of FFP and decreased administration of PRBC. A PRBC/FFP ratio of <2:1 seems to be associated with the greatest decrease in death after trauma (Holcomb JB, et al, Ann Surg 2008;248:447-58). The authors hypothesize that this should logically extend to patients with ruptured AAA who require massive transfusion. They investigated whether lesser ratios of PRBC/FFP transfusion would result in lower 30-day mortality in patients with ruptured AAA receiving massive transfusion. This was a retrospective review of patients undergoing emergent open ruptured AAA repair. Patients were included if they received >10 units of blood products before the conclusion of the operation. Data were analyzed for patient demographics, admission vital signs, perioperative variables, the amount of blood products transfused, laboratory values, and the PRBC/FFP ratio. A multivariant analysis model was used to evaluate the effects of individual variables on 30-day mortality. Of 168 patients undergoing repair of a ruptured AAA during the perioperative period, 128 patients (85% men) received at least 10 units of blood products. Mean age was 73 ± 9 years. The 30-day mortality was 22.6%, including 11 intraoperative deaths. The 30-day mortality was lower (15% vs 39%; P < .03) in patients who received transfusions with a PRBC/FFP ratio ≤ 2:1 compared with those with a ratio >2:1. Odds ratio for death in the low FFP group vs the high FFP ratio group was 4.23 (95% CI, 1.2-14.5). Patients who received transfusions with high FFP ratios had a 22.4% incidence of colon ischemia vs 41.1% in those who received transfusions with low FFP ratios (P = .004). Comment: The very low overall 30-day mortality of 22.6% in a group of patients undergoing open repair of a ruptured AAA is exemplary. Although this low mortality rate likely suggests some referral bias and transfer of patients to a regional center, the results are nonetheless excellent. The clear benefit in this study, and in the trauma literature, of a higher ratio of transfusion of FFP/PRBC in patients with massive hemorrhage strongly argues for a standardized protocol of resuscitation of patients with ruptured AAA." @default.
• W2125868049 created "2016-06-24" @default.
• W2125868049 creator A5008866393 @default.
• W2125868049 creator A5021365304 @default.
• W2125868049 creator A5088025757 @default.
• W2125868049 date "2011-04-01" @default.
• W2125868049 modified "2023-09-26" @default.
• W2125868049 title "Effect of early plasma transfusion on mortality in patients with ruptured abdominal aortic aneurysm" @default.
• W2125868049 cites W1967578007 @default.
• W2125868049 cites W1967815379 @default.
• W2125868049 cites W1972670445 @default.
• W2125868049 cites W1975962159 @default.
• W2125868049 cites W1987785121 @default.
• W2125868049 cites W1996765497 @default.
• W2125868049 cites W2003061538 @default.
• W2125868049 cites W2008363233 @default.
• W2125868049 cites W2013212009 @default.
• W2125868049 cites W2018556085 @default.
• W2125868049 cites W2024526916 @default.
• W2125868049 cites W2055034760 @default.
• W2125868049 cites W2056645952 @default.
• W2125868049 cites W2063155021 @default.
• W2125868049 cites W2068710168 @default.
• W2125868049 cites W2069340658 @default.
• W2125868049 cites W2083005745 @default.
• W2125868049 cites W2090717755 @default.
• W2125868049 cites W2091422875 @default.
• W2125868049 cites W2111676524 @default.
• W2125868049 cites W2133853192 @default.
• W2125868049 cites W2142681490 @default.
• W2125868049 cites W2146700368 @default.
• W2125868049 cites W2155688434 @default.
• W2125868049 cites W2157076733 @default.
• W2125868049 cites W2324829729 @default.
• W2125868049 doi "https://doi.org/10.1016/j.jvs.2011.02.042" @default.
• W2125868049 hasPublicationYear "2011" @default.
• W2125868049 type Work @default.
• W2125868049 sameAs 2125868049 @default.
• W2125868049 citedByCount "0" @default.
• W2125868049 crossrefType "journal-article" @default.
• W2125868049 hasAuthorship W2125868049A5008866393 @default.
• W2125868049 hasAuthorship W2125868049A5021365304 @default.
• W2125868049 hasAuthorship W2125868049A5088025757 @default.
• W2125868049 hasBestOaLocation W21258680491 @default.
• W2125868049 hasConcept C126322002 @default.
• W2125868049 hasConcept C141071460 @default.
• W2125868049 hasConcept C159641895 @default.
• W2125868049 hasConcept C167135981 @default.
• W2125868049 hasConcept C2779744138 @default.
• W2125868049 hasConcept C2780014101 @default.
• W2125868049 hasConcept C2780920261 @default.
• W2125868049 hasConcept C2781300812 @default.
• W2125868049 hasConcept C2781309813 @default.
• W2125868049 hasConcept C31174226 @default.
• W2125868049 hasConcept C42219234 @default.
• W2125868049 hasConcept C66112548 @default.
• W2125868049 hasConcept C71924100 @default.
• W2125868049 hasConcept C89560881 @default.
• W2125868049 hasConceptScore W2125868049C126322002 @default.
• W2125868049 hasConceptScore W2125868049C141071460 @default.
• W2125868049 hasConceptScore W2125868049C159641895 @default.
• W2125868049 hasConceptScore W2125868049C167135981 @default.
• W2125868049 hasConceptScore W2125868049C2779744138 @default.
• W2125868049 hasConceptScore W2125868049C2780014101 @default.
• W2125868049 hasConceptScore W2125868049C2780920261 @default.
• W2125868049 hasConceptScore W2125868049C2781300812 @default.
• W2125868049 hasConceptScore W2125868049C2781309813 @default.
• W2125868049 hasConceptScore W2125868049C31174226 @default.
• W2125868049 hasConceptScore W2125868049C42219234 @default.
• W2125868049 hasConceptScore W2125868049C66112548 @default.
• W2125868049 hasConceptScore W2125868049C71924100 @default.
• W2125868049 hasConceptScore W2125868049C89560881 @default.
• W2125868049 hasIssue "4" @default.
• W2125868049 hasLocation W21258680491 @default.
• W2125868049 hasOpenAccess W2125868049 @default.
• W2125868049 hasPrimaryLocation W21258680491 @default.
• W2125868049 hasRelatedWork W1966011210 @default.
• W2125868049 hasRelatedWork W2089836366 @default.
• W2125868049 hasRelatedWork W2107205225 @default.
• W2125868049 hasRelatedWork W2922758247 @default.
• W2125868049 hasRelatedWork W2947389589 @default.
• W2125868049 hasRelatedWork W4205266709 @default.
• W2125868049 hasRelatedWork W4244875165 @default.
• W2125868049 hasRelatedWork W4285036206 @default.
• W2125868049 hasRelatedWork W4294542926 @default.
• W2125868049 hasRelatedWork W4322495320 @default.
• W2125868049 hasVolume "53" @default.
• W2125868049 isParatext "false" @default.
• W2125868049 isRetracted "false" @default.
• W2125868049 magId "2125868049" @default.
• W2125868049 workType "article" @default.