Matches in SemOpenAlex for { <https://semopenalex.org/work/W2125951321> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2125951321 endingPage "348" @default.
- W2125951321 startingPage "345" @default.
- W2125951321 abstract "Psoriasis is a chronic inflammatory skin disease associated with an increased cardiovascular risk profile with multiple underlying factors. Psoriasis has been associated with abnormal plasma lipid metabolism and oxidative stress. Lipoprotein (a) (Lp(a)) has been implied in cardiovascular disease and has been reported to be elevated in patients with psoriasis. The present study was to determine the serum lipid disturbances and to assess the significance of Lipoprotein (a) levels in subjects with pso- riasis. 30 patients with psoriasis in the age group of 15 to 75 years were studied and compared with 30 healthy controls matched in terms of age, gender and body mass index. Serum TC, TG, VLDL-C, TC/HDL-C ratio levels were significantly higher in the psoriasis patients compared to controls. LDL-C was higher and HDL-C was lower respectively in the cases compared to controls, with the difference which was statistically insignificant. Patients with psoriasis showed significantly higher serum levels of Lp(a) compared to controls. Thus Patients with Psoriasis could be considered as a high risk group for atherosclerosis and cardiovascular diseases because of susceptibil- ity in lipid profile, Lipoprotein content and increased oxidant stress. Recent studies suggest that psoriasis, like atherosclerosis, is an autoimmune disease. The clinical manifestation of both dis- eases includes inflammation which appears to be driven by T- cell cytokines characteristic of the T-helper 1 cell response. The activation of the immune system in psoriasis cause changes in patient's lipid profile. 5 Numerous studies have demonstrated that lipoprotein (a) (Lp(a)), a genetically determined lipoprotein, is most powerful and most prevalent independent risk factor for coronary heart disease. Lp (a) is a heterogeneous lipoprotein that incorporates a low-density lipoprotein (LDL) particle and highly polymorphic apolipoprotein(a) (Apo(a)), which is cova- lently linked to the apolipoprotein B moiety of the LDL by a sin- gle disulfide bridge. 6, 7" @default.
- W2125951321 created "2016-06-24" @default.
- W2125951321 creator A5001804730 @default.
- W2125951321 creator A5055080449 @default.
- W2125951321 date "2014-09-01" @default.
- W2125951321 modified "2023-09-26" @default.
- W2125951321 title "Serum Lipids and Lipoprotein (a) Levels in Psoriasis" @default.
- W2125951321 cites W2053424469 @default.
- W2125951321 hasPublicationYear "2014" @default.
- W2125951321 type Work @default.
- W2125951321 sameAs 2125951321 @default.
- W2125951321 citedByCount "1" @default.
- W2125951321 countsByYear W21259513212015 @default.
- W2125951321 crossrefType "journal-article" @default.
- W2125951321 hasAuthorship W2125951321A5001804730 @default.
- W2125951321 hasAuthorship W2125951321A5055080449 @default.
- W2125951321 hasConcept C126322002 @default.
- W2125951321 hasConcept C134018914 @default.
- W2125951321 hasConcept C203014093 @default.
- W2125951321 hasConcept C2776104379 @default.
- W2125951321 hasConcept C2776151105 @default.
- W2125951321 hasConcept C2776914184 @default.
- W2125951321 hasConcept C2778163477 @default.
- W2125951321 hasConcept C2778270857 @default.
- W2125951321 hasConcept C2779134260 @default.
- W2125951321 hasConcept C2780072125 @default.
- W2125951321 hasConcept C2780221984 @default.
- W2125951321 hasConcept C2780564577 @default.
- W2125951321 hasConcept C4733338 @default.
- W2125951321 hasConcept C71924100 @default.
- W2125951321 hasConcept C8243546 @default.
- W2125951321 hasConcept C8891405 @default.
- W2125951321 hasConceptScore W2125951321C126322002 @default.
- W2125951321 hasConceptScore W2125951321C134018914 @default.
- W2125951321 hasConceptScore W2125951321C203014093 @default.
- W2125951321 hasConceptScore W2125951321C2776104379 @default.
- W2125951321 hasConceptScore W2125951321C2776151105 @default.
- W2125951321 hasConceptScore W2125951321C2776914184 @default.
- W2125951321 hasConceptScore W2125951321C2778163477 @default.
- W2125951321 hasConceptScore W2125951321C2778270857 @default.
- W2125951321 hasConceptScore W2125951321C2779134260 @default.
- W2125951321 hasConceptScore W2125951321C2780072125 @default.
- W2125951321 hasConceptScore W2125951321C2780221984 @default.
- W2125951321 hasConceptScore W2125951321C2780564577 @default.
- W2125951321 hasConceptScore W2125951321C4733338 @default.
- W2125951321 hasConceptScore W2125951321C71924100 @default.
- W2125951321 hasConceptScore W2125951321C8243546 @default.
- W2125951321 hasConceptScore W2125951321C8891405 @default.
- W2125951321 hasIssue "9" @default.
- W2125951321 hasLocation W21259513211 @default.
- W2125951321 hasOpenAccess W2125951321 @default.
- W2125951321 hasPrimaryLocation W21259513211 @default.
- W2125951321 hasRelatedWork W196644465 @default.
- W2125951321 hasRelatedWork W1976932407 @default.
- W2125951321 hasRelatedWork W2037617776 @default.
- W2125951321 hasRelatedWork W2072542934 @default.
- W2125951321 hasRelatedWork W2099313114 @default.
- W2125951321 hasRelatedWork W2103542940 @default.
- W2125951321 hasRelatedWork W2156782352 @default.
- W2125951321 hasRelatedWork W2162204819 @default.
- W2125951321 hasRelatedWork W2180192473 @default.
- W2125951321 hasRelatedWork W2187077117 @default.
- W2125951321 hasRelatedWork W2259949287 @default.
- W2125951321 hasRelatedWork W2325374177 @default.
- W2125951321 hasRelatedWork W2339026867 @default.
- W2125951321 hasRelatedWork W2356699526 @default.
- W2125951321 hasRelatedWork W2418940845 @default.
- W2125951321 hasRelatedWork W2587011273 @default.
- W2125951321 hasRelatedWork W2590337677 @default.
- W2125951321 hasRelatedWork W2620976079 @default.
- W2125951321 hasRelatedWork W2679566750 @default.
- W2125951321 hasRelatedWork W3028862041 @default.
- W2125951321 hasVolume "3" @default.
- W2125951321 isParatext "false" @default.
- W2125951321 isRetracted "false" @default.
- W2125951321 magId "2125951321" @default.
- W2125951321 workType "article" @default.