Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126017375> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2126017375 endingPage "234" @default.
- W2126017375 startingPage "228" @default.
- W2126017375 abstract "Aims: To evaluate safety and effectiveness of 28‐day long‐acting penicillin to prevent recurrences of acute rheumatic fever (ARF). Methods: Historical cohort study using the regional RF register for Auckland, New Zealand, in a 5–14‐year‐old population with ARF rates of ∼40–80/100 000. Consented patients were referred to a population‐based delivery programme of free benzathine penicillin every 28 days by community nurses with discharge after the longer of 10 years of treatment or aged 21 years. First‐episode and recurrent ARF cases classified as definite (Jones criteria 1992) or probable (Jones criteria 1956) were the main outcome measures. Results: Of the 360 cases meeting the case definitions, 20 recurrences occurred in 19 people (median age 21 years). The age at first episode was 2–52 years (mode 11 years), median age 21.3 (8–40). ARF recurred 0–21 years after penicillin was discontinued. Seventy‐two per cent of recurrent cases occurred within 5 years, and 12% between 5 years and 10 years. The 4‐weekly long‐acting penicillin failure rate ( n = 1) was 0.07/100 patient years. The programme failure rate (Auckland residents) was 1.4/100 patient years ( n = 20). Patient non‐adherence accounted for 55% of recurrences. Two recurrences after discharge from prophylaxis as per the New Zealand guidelines occurred 3 years and 13 years later. Conclusions: In this environment, 28‐day long‐acting penicillin prophylaxis for at least 10 years delivered by community nurses is safe and effective for patients with no or mild cardiac disease by auscultation at discharge off penicillin. Penicillin delivery every 21 days (as suggested by a recent Cochrane review) would add to costs and complexity." @default.
- W2126017375 created "2016-06-24" @default.
- W2126017375 creator A5009295901 @default.
- W2126017375 creator A5012319711 @default.
- W2126017375 creator A5065945781 @default.
- W2126017375 date "2011-04-01" @default.
- W2126017375 modified "2023-10-17" @default.
- W2126017375 title "Rheumatic fever recurrence prevention: A nurse-led programme of 28-day penicillin in an area of high endemnicity" @default.
- W2126017375 cites W1610132790 @default.
- W2126017375 cites W1637770434 @default.
- W2126017375 cites W178931190 @default.
- W2126017375 cites W1988343080 @default.
- W2126017375 cites W1992821456 @default.
- W2126017375 cites W1997945450 @default.
- W2126017375 cites W2040835603 @default.
- W2126017375 cites W2056810785 @default.
- W2126017375 cites W2058223348 @default.
- W2126017375 cites W2061363038 @default.
- W2126017375 cites W2063629299 @default.
- W2126017375 cites W2073057414 @default.
- W2126017375 cites W2074540109 @default.
- W2126017375 cites W2081578131 @default.
- W2126017375 cites W2103269964 @default.
- W2126017375 cites W2116269189 @default.
- W2126017375 cites W2117298152 @default.
- W2126017375 cites W2155634177 @default.
- W2126017375 cites W2411376695 @default.
- W2126017375 cites W4248417271 @default.
- W2126017375 doi "https://doi.org/10.1111/j.1440-1754.2010.01942.x" @default.
- W2126017375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21470327" @default.
- W2126017375 hasPublicationYear "2011" @default.
- W2126017375 type Work @default.
- W2126017375 sameAs 2126017375 @default.
- W2126017375 citedByCount "49" @default.
- W2126017375 countsByYear W21260173752012 @default.
- W2126017375 countsByYear W21260173752013 @default.
- W2126017375 countsByYear W21260173752014 @default.
- W2126017375 countsByYear W21260173752015 @default.
- W2126017375 countsByYear W21260173752016 @default.
- W2126017375 countsByYear W21260173752017 @default.
- W2126017375 countsByYear W21260173752018 @default.
- W2126017375 countsByYear W21260173752019 @default.
- W2126017375 countsByYear W21260173752020 @default.
- W2126017375 countsByYear W21260173752021 @default.
- W2126017375 countsByYear W21260173752022 @default.
- W2126017375 countsByYear W21260173752023 @default.
- W2126017375 crossrefType "journal-article" @default.
- W2126017375 hasAuthorship W2126017375A5009295901 @default.
- W2126017375 hasAuthorship W2126017375A5012319711 @default.
- W2126017375 hasAuthorship W2126017375A5065945781 @default.
- W2126017375 hasConcept C126322002 @default.
- W2126017375 hasConcept C141071460 @default.
- W2126017375 hasConcept C174802600 @default.
- W2126017375 hasConcept C187212893 @default.
- W2126017375 hasConcept C2781236483 @default.
- W2126017375 hasConcept C2908647359 @default.
- W2126017375 hasConcept C2991671097 @default.
- W2126017375 hasConcept C501593827 @default.
- W2126017375 hasConcept C71924100 @default.
- W2126017375 hasConcept C72563966 @default.
- W2126017375 hasConcept C86803240 @default.
- W2126017375 hasConcept C89423630 @default.
- W2126017375 hasConcept C99454951 @default.
- W2126017375 hasConceptScore W2126017375C126322002 @default.
- W2126017375 hasConceptScore W2126017375C141071460 @default.
- W2126017375 hasConceptScore W2126017375C174802600 @default.
- W2126017375 hasConceptScore W2126017375C187212893 @default.
- W2126017375 hasConceptScore W2126017375C2781236483 @default.
- W2126017375 hasConceptScore W2126017375C2908647359 @default.
- W2126017375 hasConceptScore W2126017375C2991671097 @default.
- W2126017375 hasConceptScore W2126017375C501593827 @default.
- W2126017375 hasConceptScore W2126017375C71924100 @default.
- W2126017375 hasConceptScore W2126017375C72563966 @default.
- W2126017375 hasConceptScore W2126017375C86803240 @default.
- W2126017375 hasConceptScore W2126017375C89423630 @default.
- W2126017375 hasConceptScore W2126017375C99454951 @default.
- W2126017375 hasIssue "4" @default.
- W2126017375 hasLocation W21260173751 @default.
- W2126017375 hasLocation W21260173752 @default.
- W2126017375 hasOpenAccess W2126017375 @default.
- W2126017375 hasPrimaryLocation W21260173751 @default.
- W2126017375 hasRelatedWork W1965535113 @default.
- W2126017375 hasRelatedWork W1977822295 @default.
- W2126017375 hasRelatedWork W2017388789 @default.
- W2126017375 hasRelatedWork W2411921660 @default.
- W2126017375 hasRelatedWork W4255110589 @default.
- W2126017375 hasRelatedWork W4256623244 @default.
- W2126017375 hasRelatedWork W4318328538 @default.
- W2126017375 hasRelatedWork W942773287 @default.
- W2126017375 hasRelatedWork W215906926 @default.
- W2126017375 hasRelatedWork W3107305858 @default.
- W2126017375 hasVolume "47" @default.
- W2126017375 isParatext "false" @default.
- W2126017375 isRetracted "false" @default.
- W2126017375 magId "2126017375" @default.
- W2126017375 workType "article" @default.