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• W2126034818 abstract "ObjectivesThis study was conducted to compare 10-year survivors with patients who survived <10 years in a large Western series of patients submitted to hepatectomy for hepatocellular carcinoma (HCC).MethodsA retrospective review of a series of hepatic resections conducted in a referral centre for HCC between January 1987 and October 2002 was conducted.ResultsA total of 176 patients were analysed. Twenty-eight patients survived ≥10 years (Group A) and were compared with the 148 patients who did not (Group B). Group A had smaller tumours (5.7cm versus 8.2cm; P = 0.001) and a lower incidence of microvascular invasion (18.5% versus 37.1%; P = 0.004). Recurrence did not differ significantly (Group A 18/28, 64.3% versus Group B 94/148, 63.5%). Median time to recurrence was longer in Group A (70 months versus 15 months; P < 0.0001), and more patients in Group A were able to undergo curative treatment for recurrence (88.8% versus 40.4%; P < 0.0001). Multivariate analysis showed that lack of vascular invasion (P = 0.020), absence of perioperative transfusion (P = 0.014), and recurrence at >2 years after primary resection (P = 0.045) were significantly associated with 10-year survival.ConclusionsTen-year survival after liver resection for HCC can be expected in approximately 15% of patients. Recurrence does not preclude longterm survival. Recurrence at >2 years after resection, absence of vascular invasion, and absence of perioperative transfusion are independently associated with 10-year survival." @default.
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• W2126034818 date "2014-09-01" @default.
• W2126034818 modified "2023-10-03" @default.
• W2126034818 title "Actual 10-year survival following hepatectomy for hepatocellular carcinoma" @default.
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• W2126034818 doi "https://doi.org/10.1111/hpb.12206" @default.
• W2126034818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4159456" @default.
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