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- W2126048596 abstract "A vast number of diseases previously considered to be of ‘unknown aetiology’ are now understood to be due to the pathogenic effects of autoimmunity (reviewed in Smith and Steinberg 1983). Owing to the pivotal role of T cells in the induction of immune responses, we have been interested in the T cells which are present and activated at sites of autoimmune reactions. As thyroid tissue is not infrequently removed at operation from patients with Graves’ disease (autoimmune hyperthyroidism), we have been able to study the lymphoid cells which are activated in vivo, express IL2 receptors, and so can be cloned. These represent an image of the disease process as it occurs in vivo (Londei et al. 1985).KeywordsCell CloneAccessory CellImmunological ToleranceUnited Kingdom CurrentCell Tolerance InductionThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W2126048596 date "1986-01-01" @default.
- W2126048596 modified "2023-09-27" @default.
- W2126048596 title "Human T Cell Clones, Tolerance, and the Analysis of Autoimmunity" @default.
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- W2126048596 doi "https://doi.org/10.1007/978-3-642-71152-7_25" @default.
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