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• W2126075609 abstract "Aim: To determine whether red cell distribution width could be used for the assessment of disease activity in patients with infl ammatory bowel disease. Materials and methods: A total of 165 patients with infl ammatory bowel disease (105 ulcerative colitis; 60 Crohn’s disease) and 43 healthy blood donors were included in this retrospective study in a tertiary care setting. Th e medical records of the patients were reviewed to note clinical activity indices, red cell distribution width, serum C reactive protein, erythrocyte sedimentation rates, leukocyte, and platelet counts. Results: Red cell distribution width, serum C reactive protein, erythrocyte sedimentation rate, platelet count, and the proportion of individuals with increased red cell distribution width were all signifi cantly elevated in the patients compared to the controls (P < 0.05). Red cell distribution width and the proportion of patients having elevated red cell distribution width were higher in patients with Crohn’s disease compared with ulcerative colitis (P < 0.05). Red cell distribution width was signifi cantly correlated with erythrocyte sedimentation rate, endoscopic activity index (in ulcerative colitis), and platelet count (P < 0.05). For a red cell distribution width cut-off of 14.45 sensitivity for diff erentiation of Crohn’s disease from ulcerative colitis was 70% and specifi city was 56%. Conclusion: Red cell distribution width, as a cost-eff ective tool, could be an additional parameter to assess disease activity in infl ammatory bowel disease and an adjunctive marker in the diff erentiation between ulcerative colitis and Crohn’s disease." @default.
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• W2126075609 date "2011-02-01" @default.
• W2126075609 modified "2023-09-23" @default.
• W2126075609 title "Th e role of red cell distribution width as a marker in infl ammatory bowel disease" @default.
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