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• W2126082102 abstract "Bacterial and host response factors play significant roles in the pathogenicity of H. pylori-related disease manifestations. The complete DNA sequences for two H. pylori strain genomes have been published. The differences in the sequences between these two unrelated strains may enable clinicians to identify rapidly other conserved and potentially virulent genes and products. Whether these two DNA sequences are sufficient representation of the H. pylori genetic heterogeneity is unknown. The host immune response and the cascade of events that occurs with H. pylori infection are being clarified rapidly. Understanding the role of this gastric bacterium in apoptosis and cellular proliferation would enable clinicians to understand its relationship to ulcerogenesis and gastric malignancy. Piecing together many observations related to H. pylori would result in understanding the interaction of H. pylori factors and host responses that lead to the variety of disease manifestations associated with this chronic infection. The development of animal models with H. pylori and other Helicobacter species has set the stage in which in vitro observations can be tested in the in vivo model." @default.
• W2126082102 created "2016-06-24" @default.
• W2126082102 creator A5033108318 @default.
• W2126082102 creator A5068507665 @default.
• W2126082102 date "2000-09-01" @default.
• W2126082102 modified "2023-10-14" @default.
• W2126082102 title "VIRULENCE AND PATHOGENICITY OF HELICOBACTER PYLORI" @default.
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• W2126082102 doi "https://doi.org/10.1016/s0889-8553(05)70136-9" @default.
• W2126082102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11030079" @default.
• W2126082102 hasPublicationYear "2000" @default.
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