FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126129152> ?p ?o ?g. }

• W2126129152 endingPage "1592" @default.
• W2126129152 startingPage "1586" @default.
• W2126129152 abstract "Background. The purpose of our study was to assess the early effects of a potent anabolic androgen on muscle mass and strength, lower extremity power, and functional performance in older men. Methods. Thirty-two men 72 ± 6 years of age were randomized to receive oxandrolone (10 mg twice daily) or matching placebo in a 2:1 manner for 12 weeks. Total and appendicular lean body mass (LBM) were assessed by dual-energy x-ray absorptiometry (DEXA). Lower extremity muscle volume was determined by magnetic resonance imaging to validate DEXA changes. Results. Total LBM increased by 2.7 ± 1.6 kg after 6 weeks with oxandrolone (p <.001), which was greater (p <.001) than the decline in LBM (−0.5 ± 0.9 kg) with placebo. Appendicular LBM increased by 1.2 ± 0.9 kg after just 6 weeks with oxandrolone (p <.001), which was greater (p <.001) than the decline in LBM (−0.4 ± 0.5 kg) with placebo. These changes were >90% of the gains in total and appendicular LBM (3.0 ± 1.5 kg and 1.3 ± 0.9 kg, respectively) after 12 weeks. Total thigh and hamstring muscle volume increased by 111 ± 29 mm3 (p =.001) and 75 ± 18 mm3 (p =.001), respectively, after 12 weeks. Maximal strength increased for the leg press 6.3 ± 5.6% (p =.003), leg curl 6.7 ± 8.6% (p =.01), chest press 6.9 ± 6.5% (p =.001), and latissimus pull-down 4.8 ± 6.3% (p =.009) with oxandrolone after 6 weeks; these increases were different than those with placebo (p <.001) and were 93%, 96%, 74%, and 94% of the respective gains at week 12. There were no improvements in functional measures. Conclusion. Treatment with a potent anabolic androgen may produce significant increases in muscle mass and strength after only 6 weeks in healthy older men. However, such treatment did not improve leg muscle power or walking speed." @default.
• W2126129152 created "2016-06-24" @default.
• W2126129152 creator A5028874871 @default.
• W2126129152 creator A5042178231 @default.
• W2126129152 creator A5046279267 @default.
• W2126129152 creator A5052976966 @default.
• W2126129152 creator A5057933988 @default.
• W2126129152 creator A5058875385 @default.
• W2126129152 creator A5078106495 @default.
• W2126129152 creator A5079866604 @default.
• W2126129152 date "2005-12-01" @default.
• W2126129152 modified "2023-10-10" @default.
• W2126129152 title "Six-Week Improvements in Muscle Mass and Strength During Androgen Therapy in Older Men" @default.
• W2126129152 cites W1556303558 @default.
• W2126129152 cites W1894626861 @default.
• W2126129152 cites W1987847353 @default.
• W2126129152 cites W1989458934 @default.
• W2126129152 cites W2023324665 @default.
• W2126129152 cites W2028873090 @default.
• W2126129152 cites W2042178933 @default.
• W2126129152 cites W2045724757 @default.
• W2126129152 cites W2049699863 @default.
• W2126129152 cites W2061933138 @default.
• W2126129152 cites W2071205972 @default.
• W2126129152 cites W2084691633 @default.
• W2126129152 cites W2098544119 @default.
• W2126129152 cites W2104357394 @default.
• W2126129152 cites W2107168102 @default.
• W2126129152 cites W2111938618 @default.
• W2126129152 cites W2115041062 @default.
• W2126129152 cites W2127219068 @default.
• W2126129152 cites W2129322604 @default.
• W2126129152 cites W2133685760 @default.
• W2126129152 cites W2136743230 @default.
• W2126129152 cites W2143637259 @default.
• W2126129152 cites W2149311704 @default.
• W2126129152 cites W2161349877 @default.
• W2126129152 cites W2184656706 @default.
• W2126129152 cites W2185952775 @default.
• W2126129152 cites W3143060430 @default.
• W2126129152 cites W4232635137 @default.
• W2126129152 cites W4233478829 @default.
• W2126129152 cites W4233841204 @default.
• W2126129152 cites W4241382776 @default.
• W2126129152 cites W4246208375 @default.
• W2126129152 cites W4251071461 @default.
• W2126129152 cites W4254441152 @default.
• W2126129152 cites W4255449971 @default.
• W2126129152 doi "https://doi.org/10.1093/gerona/60.12.1586" @default.
• W2126129152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16424293" @default.
• W2126129152 hasPublicationYear "2005" @default.
• W2126129152 type Work @default.
• W2126129152 sameAs 2126129152 @default.
• W2126129152 citedByCount "31" @default.
• W2126129152 countsByYear W21261291522012 @default.
• W2126129152 countsByYear W21261291522013 @default.
• W2126129152 countsByYear W21261291522014 @default.
• W2126129152 countsByYear W21261291522015 @default.
• W2126129152 countsByYear W21261291522017 @default.
• W2126129152 countsByYear W21261291522018 @default.
• W2126129152 countsByYear W21261291522019 @default.
• W2126129152 countsByYear W21261291522020 @default.
• W2126129152 countsByYear W21261291522022 @default.
• W2126129152 countsByYear W21261291522023 @default.
• W2126129152 crossrefType "journal-article" @default.
• W2126129152 hasAuthorship W2126129152A5028874871 @default.
• W2126129152 hasAuthorship W2126129152A5042178231 @default.
• W2126129152 hasAuthorship W2126129152A5046279267 @default.
• W2126129152 hasAuthorship W2126129152A5052976966 @default.
• W2126129152 hasAuthorship W2126129152A5057933988 @default.
• W2126129152 hasAuthorship W2126129152A5058875385 @default.
• W2126129152 hasAuthorship W2126129152A5078106495 @default.
• W2126129152 hasAuthorship W2126129152A5079866604 @default.
• W2126129152 hasBestOaLocation W21261291521 @default.
• W2126129152 hasConcept C120863210 @default.
• W2126129152 hasConcept C126322002 @default.
• W2126129152 hasConcept C126894567 @default.
• W2126129152 hasConcept C134018914 @default.
• W2126129152 hasConcept C142724271 @default.
• W2126129152 hasConcept C147583825 @default.
• W2126129152 hasConcept C204787440 @default.
• W2126129152 hasConcept C27081682 @default.
• W2126129152 hasConcept C2776214593 @default.
• W2126129152 hasConcept C2779733885 @default.
• W2126129152 hasConcept C2984496839 @default.
• W2126129152 hasConcept C71315377 @default.
• W2126129152 hasConcept C71924100 @default.
• W2126129152 hasConceptScore W2126129152C120863210 @default.
• W2126129152 hasConceptScore W2126129152C126322002 @default.
• W2126129152 hasConceptScore W2126129152C126894567 @default.
• W2126129152 hasConceptScore W2126129152C134018914 @default.
• W2126129152 hasConceptScore W2126129152C142724271 @default.
• W2126129152 hasConceptScore W2126129152C147583825 @default.
• W2126129152 hasConceptScore W2126129152C204787440 @default.
• W2126129152 hasConceptScore W2126129152C27081682 @default.
• W2126129152 hasConceptScore W2126129152C2776214593 @default.
• W2126129152 hasConceptScore W2126129152C2779733885 @default.
• W2126129152 hasConceptScore W2126129152C2984496839 @default.

• next