Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126232452> ?p ?o ?g. }
- W2126232452 endingPage "6" @default.
- W2126232452 startingPage "2081" @default.
- W2126232452 abstract "Three men, aged 39, 73, and 66 years, respectively, developed an infection with a new strain ofClostridium difficile, ribotype 027.C.difficile-associated diarrhoea (CDAD) occurred in two patients after multiple abdominal surgery and in the third patient one week after autologous haematopoietic cell transplantation. Within a few days, despite antibiotic therapy, all three patients developed severe (pseudomembranous) colitis with sepsis for which admission to the Intensive Care Unit was required. Two patients underwent (sub)total colectomy and received an intensive course of oral and/or rectal vancomycin. In all patients who develop diarrhoea in hospital, especially during or after treatment with antibiotics or chemotherapeutic agents, an infection with C. difficile ribotype 027 should be suspected. Recent outbreaks of this hypervirulent strain of C. difficile have been reported in Canada, the United States, United Kingdom, and The Netherlands. Demonstration of C. difficile toxin in faeces confirms the clinical suspicion of CDAD and ribotyping of the strain may reveal whether the 027 strain is present. For treatment of these 027 infections, vancomycin is preferred to metronidazole. After a severe course of colitis or in case of recurrence a 'tapering and pulse' course ofvancomycin can be prescribed; alternatively, treatment with bovine antibody-enriched whey may be considered. The introduction of this hypervirulent strain has led to reinforcement of the hygienic measures in accordance with the recommendations of the Dutch Working Party on Infection Prevention and a policy to deter the use of fluoroquinolones." @default.
- W2126232452 created "2016-06-24" @default.
- W2126232452 creator A5032564619 @default.
- W2126232452 creator A5034782355 @default.
- W2126232452 creator A5047301490 @default.
- W2126232452 creator A5050386661 @default.
- W2126232452 creator A5073216767 @default.
- W2126232452 creator A5075491700 @default.
- W2126232452 date "2005-09-17" @default.
- W2126232452 modified "2023-09-26" @default.
- W2126232452 title "[Life-threatening infections with a new strain of Clostridium difficile]." @default.
- W2126232452 cites W1436853918 @default.
- W2126232452 cites W1503473328 @default.
- W2126232452 cites W1981518376 @default.
- W2126232452 cites W1994090985 @default.
- W2126232452 cites W2051223662 @default.
- W2126232452 cites W2056233231 @default.
- W2126232452 cites W2066547211 @default.
- W2126232452 cites W2102459023 @default.
- W2126232452 cites W2107295643 @default.
- W2126232452 cites W2109743785 @default.
- W2126232452 cites W2115419460 @default.
- W2126232452 cites W2117604887 @default.
- W2126232452 cites W2120136295 @default.
- W2126232452 cites W2125343055 @default.
- W2126232452 cites W2129946284 @default.
- W2126232452 cites W2140653473 @default.
- W2126232452 cites W2143849824 @default.
- W2126232452 cites W2150765371 @default.
- W2126232452 cites W2160486943 @default.
- W2126232452 cites W2163918813 @default.
- W2126232452 cites W2166223093 @default.
- W2126232452 cites W2167717276 @default.
- W2126232452 cites W2167766152 @default.
- W2126232452 cites W2318911370 @default.
- W2126232452 cites W2436363974 @default.
- W2126232452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16201595" @default.
- W2126232452 hasPublicationYear "2005" @default.
- W2126232452 type Work @default.
- W2126232452 sameAs 2126232452 @default.
- W2126232452 citedByCount "3" @default.
- W2126232452 crossrefType "journal-article" @default.
- W2126232452 hasAuthorship W2126232452A5032564619 @default.
- W2126232452 hasAuthorship W2126232452A5034782355 @default.
- W2126232452 hasAuthorship W2126232452A5047301490 @default.
- W2126232452 hasAuthorship W2126232452A5050386661 @default.
- W2126232452 hasAuthorship W2126232452A5073216767 @default.
- W2126232452 hasAuthorship W2126232452A5075491700 @default.
- W2126232452 hasConcept C126322002 @default.
- W2126232452 hasConcept C177713679 @default.
- W2126232452 hasConcept C2775862500 @default.
- W2126232452 hasConcept C2776258884 @default.
- W2126232452 hasConcept C2776376669 @default.
- W2126232452 hasConcept C2776611563 @default.
- W2126232452 hasConcept C2776667177 @default.
- W2126232452 hasConcept C2777396551 @default.
- W2126232452 hasConcept C2778980435 @default.
- W2126232452 hasConcept C2779134260 @default.
- W2126232452 hasConcept C2779489039 @default.
- W2126232452 hasConcept C2780479503 @default.
- W2126232452 hasConcept C2991793726 @default.
- W2126232452 hasConcept C2994496256 @default.
- W2126232452 hasConcept C501593827 @default.
- W2126232452 hasConcept C523546767 @default.
- W2126232452 hasConcept C54355233 @default.
- W2126232452 hasConcept C71924100 @default.
- W2126232452 hasConcept C86803240 @default.
- W2126232452 hasConcept C89423630 @default.
- W2126232452 hasConceptScore W2126232452C126322002 @default.
- W2126232452 hasConceptScore W2126232452C177713679 @default.
- W2126232452 hasConceptScore W2126232452C2775862500 @default.
- W2126232452 hasConceptScore W2126232452C2776258884 @default.
- W2126232452 hasConceptScore W2126232452C2776376669 @default.
- W2126232452 hasConceptScore W2126232452C2776611563 @default.
- W2126232452 hasConceptScore W2126232452C2776667177 @default.
- W2126232452 hasConceptScore W2126232452C2777396551 @default.
- W2126232452 hasConceptScore W2126232452C2778980435 @default.
- W2126232452 hasConceptScore W2126232452C2779134260 @default.
- W2126232452 hasConceptScore W2126232452C2779489039 @default.
- W2126232452 hasConceptScore W2126232452C2780479503 @default.
- W2126232452 hasConceptScore W2126232452C2991793726 @default.
- W2126232452 hasConceptScore W2126232452C2994496256 @default.
- W2126232452 hasConceptScore W2126232452C501593827 @default.
- W2126232452 hasConceptScore W2126232452C523546767 @default.
- W2126232452 hasConceptScore W2126232452C54355233 @default.
- W2126232452 hasConceptScore W2126232452C71924100 @default.
- W2126232452 hasConceptScore W2126232452C86803240 @default.
- W2126232452 hasConceptScore W2126232452C89423630 @default.
- W2126232452 hasIssue "38" @default.
- W2126232452 hasLocation W21262324521 @default.
- W2126232452 hasOpenAccess W2126232452 @default.
- W2126232452 hasPrimaryLocation W21262324521 @default.
- W2126232452 hasRelatedWork W1931380669 @default.
- W2126232452 hasRelatedWork W1990340449 @default.
- W2126232452 hasRelatedWork W2043641411 @default.
- W2126232452 hasRelatedWork W2043678651 @default.
- W2126232452 hasRelatedWork W2057717979 @default.
- W2126232452 hasRelatedWork W2058867048 @default.