Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126259712> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2126259712 endingPage "1826" @default.
- W2126259712 startingPage "1819" @default.
- W2126259712 abstract "Patients with fatal asthma have been hypothesized as representing two distinct subgroups according to the onset of symptoms prior to death.To determine if these two groups may be reliably identified and determine if they differ clinically and pathologically.Patients with autopsies, 2-34 years of age, dying from asthma were classified slow-onset (Type 1) or rapid-onset (Type 2). The consistency of classification by two independent observers was determined. Clinical and pathologic data was compared between groups.Among 37 subjects there were 21 Type 1 and 16 Type 2 mortalities. Inter-observer agreement was good; kappa 0.63 (95% CI 0.38, 0.87). Subjects did not differ by age, race, sex, presence of obesity, insurance status, or use of corticosteroids. Type 1 mortalities were hospitalized more (2.5+1.3 versus 0.1+0.1; p=0.048) and made more emergency room visits (10.5+4.9 versus 0.8+0.2; p=0.023) in the year prior to death than Type 2 mortalities. At autopsy, bronchial eosinophils (p<0.025) and bronchiolar basement membrane thickening (p<0.05) were more predominant in Type 1 mortalities compared with Type 2. Airway wall neutrophils were uncommon in both groups.Good inter-observer agreement exists in classifying patients dying from asthma according to whether the onset of symptoms was slow or rapid in onset. Slow-onset patients had a predominance of eosinophils and basement membrane thickening and higher health care utilization. These differences support the validity of classifying asthma mortalities into these distinct subgroups." @default.
- W2126259712 created "2016-06-24" @default.
- W2126259712 creator A5009848347 @default.
- W2126259712 creator A5010115182 @default.
- W2126259712 creator A5013704262 @default.
- W2126259712 creator A5044483075 @default.
- W2126259712 creator A5054826116 @default.
- W2126259712 creator A5084918533 @default.
- W2126259712 date "2008-12-01" @default.
- W2126259712 modified "2023-09-24" @default.
- W2126259712 title "Slow-onset asthma deaths have more eosinophils and health care utilization than rapid-onset deaths" @default.
- W2126259712 cites W1903161601 @default.
- W2126259712 cites W1967023776 @default.
- W2126259712 cites W1979704535 @default.
- W2126259712 cites W1982336794 @default.
- W2126259712 cites W1993900221 @default.
- W2126259712 cites W1993997407 @default.
- W2126259712 cites W1999092751 @default.
- W2126259712 cites W1999159110 @default.
- W2126259712 cites W1999226173 @default.
- W2126259712 cites W2009722639 @default.
- W2126259712 cites W2016323466 @default.
- W2126259712 cites W2019609817 @default.
- W2126259712 cites W2042820847 @default.
- W2126259712 cites W2047042060 @default.
- W2126259712 cites W2059287406 @default.
- W2126259712 cites W2081256353 @default.
- W2126259712 cites W2093025649 @default.
- W2126259712 cites W2094714142 @default.
- W2126259712 cites W2096112886 @default.
- W2126259712 cites W2096431450 @default.
- W2126259712 cites W2103089644 @default.
- W2126259712 cites W2106178073 @default.
- W2126259712 cites W2110921365 @default.
- W2126259712 cites W2113012453 @default.
- W2126259712 cites W2113290544 @default.
- W2126259712 cites W2123624814 @default.
- W2126259712 cites W2133328383 @default.
- W2126259712 cites W2136576396 @default.
- W2126259712 cites W2145569721 @default.
- W2126259712 cites W2157368871 @default.
- W2126259712 cites W2157676234 @default.
- W2126259712 cites W2164749658 @default.
- W2126259712 cites W2308777632 @default.
- W2126259712 cites W4247475865 @default.
- W2126259712 doi "https://doi.org/10.1016/j.rmed.2008.06.011" @default.
- W2126259712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18692379" @default.
- W2126259712 hasPublicationYear "2008" @default.
- W2126259712 type Work @default.
- W2126259712 sameAs 2126259712 @default.
- W2126259712 citedByCount "12" @default.
- W2126259712 countsByYear W21262597122012 @default.
- W2126259712 countsByYear W21262597122014 @default.
- W2126259712 countsByYear W21262597122016 @default.
- W2126259712 countsByYear W21262597122017 @default.
- W2126259712 countsByYear W21262597122019 @default.
- W2126259712 countsByYear W21262597122020 @default.
- W2126259712 countsByYear W21262597122021 @default.
- W2126259712 crossrefType "journal-article" @default.
- W2126259712 hasAuthorship W2126259712A5009848347 @default.
- W2126259712 hasAuthorship W2126259712A5010115182 @default.
- W2126259712 hasAuthorship W2126259712A5013704262 @default.
- W2126259712 hasAuthorship W2126259712A5044483075 @default.
- W2126259712 hasAuthorship W2126259712A5054826116 @default.
- W2126259712 hasAuthorship W2126259712A5084918533 @default.
- W2126259712 hasBestOaLocation W21262597121 @default.
- W2126259712 hasConcept C126322002 @default.
- W2126259712 hasConcept C187212893 @default.
- W2126259712 hasConcept C2776042228 @default.
- W2126259712 hasConcept C2779504383 @default.
- W2126259712 hasConcept C71924100 @default.
- W2126259712 hasConceptScore W2126259712C126322002 @default.
- W2126259712 hasConceptScore W2126259712C187212893 @default.
- W2126259712 hasConceptScore W2126259712C2776042228 @default.
- W2126259712 hasConceptScore W2126259712C2779504383 @default.
- W2126259712 hasConceptScore W2126259712C71924100 @default.
- W2126259712 hasIssue "12" @default.
- W2126259712 hasLocation W21262597121 @default.
- W2126259712 hasLocation W21262597122 @default.
- W2126259712 hasOpenAccess W2126259712 @default.
- W2126259712 hasPrimaryLocation W21262597121 @default.
- W2126259712 hasRelatedWork W1586496696 @default.
- W2126259712 hasRelatedWork W1971365844 @default.
- W2126259712 hasRelatedWork W1994424799 @default.
- W2126259712 hasRelatedWork W1996493383 @default.
- W2126259712 hasRelatedWork W2089552687 @default.
- W2126259712 hasRelatedWork W2102017858 @default.
- W2126259712 hasRelatedWork W2305387575 @default.
- W2126259712 hasRelatedWork W2413601927 @default.
- W2126259712 hasRelatedWork W2474482116 @default.
- W2126259712 hasRelatedWork W4322724676 @default.
- W2126259712 hasVolume "102" @default.
- W2126259712 isParatext "false" @default.
- W2126259712 isRetracted "false" @default.
- W2126259712 magId "2126259712" @default.
- W2126259712 workType "article" @default.