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- W2126321103 abstract "No AccessJournal of UrologyClinical Urology: Original Articles1 Dec 1997PELVIC FLOOR ELECTRICAL STIMULATION IN THE TREATMENT OF STRESS INCONTINENCE: AN INVESTIGATIONAL STUDY AND A PLACEBO CONTROLLED DOUBLE-BLIND TRIAL Tomonori Yamanishi, Kosaku Yasuda, Ryuuji Sakakibara, Takamichi Hattori, Haruo Ito, and Shino Murakami Tomonori YamanishiTomonori Yamanishi More articles by this author , Kosaku YasudaKosaku Yasuda More articles by this author , Ryuuji SakakibaraRyuuji Sakakibara More articles by this author , Takamichi HattoriTakamichi Hattori More articles by this author , Haruo ItoHaruo Ito More articles by this author , and Shino MurakamiShino Murakami More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)68176-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We designed an investigational study and a placebo controlled, double-blind study to evaluate the usefulness of electrical pelvic stimulation in stress incontinence. Materials and Methods: We studied 44 patients with stress incontinence (six men and 38 women, age 63 +/− 13), including 9 patients in the investigational study and 35 in the double-blind study. We used 50 Hz. square waves of 1 ms. pulse duration for stimulation. A vaginal electrode was used in women and an anal electrode in men. Urethral pressure profile before, during and after 15-minute stimulation was measured in the investigational study. In the double-blind trial an active device and a dummy device were used, and efficacy was judged from patient impressions, records in frequency/volume chart, results of 1-hour pad test and urodynamic parameters after 4-week treatment. Results: In the investigational study maximum urethral closure pressure (mean plus or minus standard deviation) before, during and after stimulation was 44.4 +/− 17.5, 64.5 +/− 28.8 and 46.8 +/− 25.6 cm. water, respectively. This parameter significantly increased (p = 0.0275) during stimulation. In the double-blind trial patient impressions were good in 60% of the active device group and 8% of the dummy device group (p = 0.0051). For the pad test significant improvement was noted in the active device group (p = 0.0100). Cure rate was 45% in the active device group and 7.7% in the dummy device group. There were significantly more cured or improved patients for frequency of leakage (p = 0.0196) and pad test (p = 0.0100). Conclusions: Electrical stimulation is effective for the treatment of stress incontinence. References 1 : Long term electrostimulation of the pelvic floor: primary therapy in female stress incontinence.. Urol. Int.1989; 44: 90. Google Scholar 2 : Effect of anal electrostimulation with the Incontan device in women with urinary incontinence.. Brit. J. Obst. Gynaec.1987; 94: 147. Google Scholar 3 : Pelvic floor electrical stimulation in the treatment of genuine stress incontinence: A multicenter, placebo-controlled trial.. Amer. J. Obst. Gynec.1995; 173: 72. 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Link, Google Scholar 10 : Ephedrine in treatment of urinary incontinence.. Urology1975; 5: 624. Google Scholar 11 : Pharmacologic treatment of incontinence.. J.A.G.S.1990; 38: 317. Google Scholar 12 : Double-blind clinical trial of a B2-adrenergic agonist in stress incontinence.. Int. Urogynec. J.1993; 4: 146. Google Scholar 13 : Effects of beta sub 2-stimulants on contractility and fatigue of canine urethral sphincter.. J. Urol.1994; 151: 1066. Abstract, Google Scholar 14 : Electrical stimulation for urinary incontinence.. Urol. Int.1974; 29: 213. Google Scholar 15 : Electrical pelvic floor stimulation. Mechanism of action.. Invest. Urol.1977; 15: 65. Google Scholar 16 : The effect of intravaginal electrical stimulation on the feline urethra and urinary bladder. Electrical parameters.. Scand. J. Urol. Nephrol.1978; 44: 5. Google Scholar 17 : Adjustable nonimplantable electrical stimulators for correction of urinary incontinence.. Urol. Int.1976; 31: 115. Google Scholar 18 : Urethral and bladder responses to anal electrical stimulation.. J. Urol.1978; 122: 192. Google Scholar 19 : Contelle: pelvic floor stimulator for female stress-urge incontinence. A multi center study.. Urology1986; 27: 282. Google Scholar 20 : Long-term intravaginal electrical stimulation in urge and stress incontinence.. Scand. J. Urol. Nephrol.1978; 44. Google Scholar From the Departments of Urology and Neurology, Chiba University School of Medicine, Chiba and Asahi General Hospital, Asahi, Japan.Accepted for publication June 6, 1997.Supported in part by grants from the National Research and Development for Medical and Welfare Apparatus under Industrial Science and Technology Frontier Program of the Agency of Industrial Science and Technology of the Ministry of International Trade and Industry and the New Energy and Industrial Technology Development Organization of Japan.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byYamanishi T, Mizuno T, Watanabe M, Honda M and Yoshida K (2018) Randomized, Placebo Controlled Study of Electrical Stimulation With Pelvic Floor Muscle Training for Severe Urinary Incontinence After Radical ProstatectomyJournal of Urology, VOL. 184, NO. 5, (2007-2012), Online publication date: 1-Nov-2010.ALMEIDA F, BRUSCHINI H and SROUGI M (2018) URODYNAMIC AND CLINICAL EVALUATION OF 91 FEMALE PATIENTS WITH URINARY INCONTINENCE TREATED WITH PERINEAL MAGNETIC STIMULATION: 1-YEAR FOLLOWUPJournal of Urology, VOL. 171, NO. 4, (1571-1575), Online publication date: 1-Apr-2004.FUJISHIRO T, ENOMOTO H, UGAWA Y, TAKAHASHI S, UENO S and KITAMURA T (2018) MAGNETIC STIMULATION OF THE SACRAL ROOTS FOR THE TREATMENT OF STRESS INCONTINENCE: AN INVESTIGATIONAL STUDY AND PLACEBO CONTROLLED TRIALJournal of Urology, VOL. 164, NO. 4, (1277-1279), Online publication date: 1-Oct-2000.YAMANISHI T, YASUDA K, SUDA S, ISHIKAWA N, SAKAKIBARA R and HATTORI T (2018) EFFECT OF FUNCTIONAL CONTINUOUS MAGNETIC STIMULATION FOR URINARY INCONTINENCEJournal of Urology, VOL. 163, NO. 2, (456-459), Online publication date: 1-Feb-2000. Volume 158Issue 6December 1997Page: 2127-2131 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Tomonori Yamanishi More articles by this author Kosaku Yasuda More articles by this author Ryuuji Sakakibara More articles by this author Takamichi Hattori More articles by this author Haruo Ito More articles by this author Shino Murakami More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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