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• W2126345261 abstract "In recent years concern over the adverse effects of low concentrations of lead on children has increased. In 1991, the CDC reduced the acceptable blood lead concentration from 250 μg/L to 100 μg/L and recommended screening of all American children <6 years old for lead poisoning (1). Graphite furnace atomic absorption spectroscopy is the most common method of measuring lead in blood, but the CDC has encouraged the development of other methods that could be used for mass population screening or near-patient testing. Such methods should be portable, cheap, and easier to use than graphite furnace atomic absorption spectroscopy as recommended by CDC Program Announcement 269, 1992.The electrochemical technique of stripping voltametry at a mercury electrode has also been used for blood lead analysis. Commercially available instruments based on this method have been used widely but have insufficient accuracy and precision for measuring lead at low concentrations (2). Recently, improvements have been made in the electrochemical measurement of blood lead. Ostapczuk (3) and Jagner et al. (4) obtained good accuracy and precision at low concentrations by potentiometric stripping analysis. They used a mercury-coated graphite electrode that must be cleaned between each analysis, and their testing procedure required stirring of the acidified blood solution.An approach to stripping analysis that simplifies the testing is the use of disposable electrodes, which can be used once and then thrown away. Microarray electrodes have properties that make them especially suitable for this application. They have high current densities in unstirred solution, have a high signal-to-background ratio, and are not affected …" @default.
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• W2126345261 date "1997-11-01" @default.
• W2126345261 modified "2023-09-27" @default.
• W2126345261 title "Convenient, Rapid Test for Lead in Blood with Use of Disposable Electrodes" @default.
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• W2126345261 doi "https://doi.org/10.1093/clinchem/43.11.2187" @default.
• W2126345261 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9365409" @default.
• W2126345261 hasPublicationYear "1997" @default.
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