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• W2126401449 abstract "Objective Pregnancy is characterized by progressive insulin resistance. The present study evaluated whether the adiponectin/leptin ratio is associated with insulin resistance in pregnancy, since this ratio has been shown to be associated with insulin resistance in obesity, type 2 diabetes mellitus, metabolic syndrome and polycystic ovary syndrome. Methods In this cross-sectional study, adiponectin and leptin concentrations were measured in pregnant women using enzyme-linked immunosorbent assays. Insulin resistance was assessed using the homeostasis model assessment of insulin resistance (HOMA–IR). Results Mean ± SD age of the participants ( n = 74) was 30.76 ± 4.27 years, mean ± SD gestational age was 26.81 ± 3.52 weeks and median body mass index (BMI) before pregnancy was 22.68 kg/m 2 (interquartile range 20.75–26.79 kg/m 2 ). There was a significant correlation between the HOMA–IR and leptin concentration, but not between the HOMA–IR and adiponectin concentration. There was a significant inverse correlation between the HOMA–IR and adiponectin/leptin ratio. The adiponectin/leptin ratio was inversely correlated with BMI before pregnancy. Conclusion The adiponection/leptin ratio inversely correlates with HOMA–IR in pregnancy." @default.
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• W2126401449 date "2013-01-23" @default.
• W2126401449 modified "2023-09-27" @default.
• W2126401449 title "Adiponectin/leptin ratio and insulin resistance in pregnancy" @default.
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• W2126401449 doi "https://doi.org/10.1177/0300060513476409" @default.
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