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- W2126448801 abstract "Beta-diethylaminoethyl cumate was found to be somewhat more toxic than procaine as a local anesthetic. Its acute toxicity in mice was less than that of procaine. It was also more potent than procaine on the basis of effective concentrations as determined in human intradermal tests. Given by subarachnoid injection in rabbits, little, if any, difference in spinal anesthetic potency was observed. The LD by intraperitoneal injection in mice was determined. Procaine hydrochloride was definitely less irritating than the cumate ester as determined by human intradermal tests, application to the rabbit eye, and by the trypan blue skin irritation test of Hoppe, et al." @default.
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- W2126448801 date "1957-03-01" @default.
- W2126448801 modified "2023-09-26" @default.
- W2126448801 title "A Comparative Study of the Local Anesthetic Potencies and Toxicities of Beta-Diethylaminoethyl Cumate and Procaine**College of Pharmacy, University of Florida, Gainesville" @default.
- W2126448801 doi "https://doi.org/10.1002/jps.3030460306" @default.
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