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- W2126450863 abstract "This study evaluated the quality and the remodeling of bone around commercially pure titanium implants after 3, 6, 12 and 18 month implantation periods in the sheep.Twelve animals were implanted in the cortico-trabecular areas of both femurs. Each femur received four implants with a rough surface (type 1) in the right femur and four with a smooth surface (type 2) in the left one. Bone blocks containing the implants were studied by histomorphometry on undecalcified specimens. The amount of bone around implants was measured (bone volume, fractional woven bone volume, bone thickness, contact interface) together with osteoblastic activity (mineral apposition rates, bone formation rates) and resorption activity (eroded surfaces).No significant differences could be observed for the two types of implants between 3 and 6 months. At 12 and 18 months, bone volume and contact interface were still increasing and there was always a tendency for type 1 implants to be associated with higher values. On the contrary, mineral apposition rate, bone formation rates and eroded surfaces decreased in the referent area in contact with the implant; this phenomenon of 'return to the normal' was more evident with type 1 implants. The remodeling process appears to increase bone quality and bone-titanium interface around implants in long term periods.The net bone quantity necessary to immobilize implants is obtained rapidly but the adapting process to mechanical strength can lead to a small but persistent increase in bone volume around implants. Although the differences between type 1 and type 2 implants were often small or statistically insignificant, the rougher type 1 implants seemed to be associated with stronger bone response." @default.
- W2126450863 created "2016-06-24" @default.
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- W2126450863 date "2002-07-01" @default.
- W2126450863 modified "2023-09-27" @default.
- W2126450863 title "Enhanced bone integration of implants with increased surface roughness: a long term study in the sheep" @default.
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- W2126450863 doi "https://doi.org/10.1016/s0300-5712(02)00018-0" @default.
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