FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126456089> ?p ?o ?g. }

• W2126456089 endingPage "bau076" @default.
• W2126456089 startingPage "bau076" @default.
• W2126456089 abstract "Alternative polyadenylation (APA) is a widespread mechanism that contributes to the sophisticated dynamics of gene regulation. Approximately 50% of all protein-coding human genes harbor multiple polyadenylation (PA) sites; their selective and combinatorial use gives rise to transcript variants with differing length of their 3' untranslated region (3'UTR). Shortened variants escape UTR-mediated regulation by microRNAs (miRNAs), especially in cancer, where global 3'UTR shortening accelerates disease progression, dedifferentiation and proliferation. Here we present APADB, a database of vertebrate PA sites determined by 3' end sequencing, using massive analysis of complementary DNA ends. APADB provides (A)PA sites for coding and non-coding transcripts of human, mouse and chicken genes. For human and mouse, several tissue types, including different cancer specimens, are available. APADB records the loss of predicted miRNA binding sites and visualizes next-generation sequencing reads that support each PA site in a genome browser. The database tables can either be browsed according to organism and tissue or alternatively searched for a gene of interest. APADB is the largest database of APA in human, chicken and mouse. The stored information provides experimental evidence for thousands of PA sites and APA events. APADB combines 3' end sequencing data with prediction algorithms of miRNA binding sites, allowing to further improve prediction algorithms. Current databases lack correct information about 3'UTR lengths, especially for chicken, and APADB provides necessary information to close this gap. Database URL: http://tools.genxpro.net/apadb/." @default.
• W2126456089 created "2016-06-24" @default.
• W2126456089 creator A5002656480 @default.
• W2126456089 creator A5015346451 @default.
• W2126456089 creator A5026407317 @default.
• W2126456089 creator A5040021244 @default.
• W2126456089 creator A5046342878 @default.
• W2126456089 creator A5055755552 @default.
• W2126456089 creator A5056481154 @default.
• W2126456089 creator A5066100182 @default.
• W2126456089 creator A5066983733 @default.
• W2126456089 creator A5074063240 @default.
• W2126456089 creator A5079464681 @default.
• W2126456089 date "2014-07-22" @default.
• W2126456089 modified "2023-10-01" @default.
• W2126456089 title "APADB: a database for alternative polyadenylation and microRNA regulation events" @default.
• W2126456089 cites W1964727443 @default.
• W2126456089 cites W1979537172 @default.
• W2126456089 cites W1982675984 @default.
• W2126456089 cites W1983894828 @default.
• W2126456089 cites W1984397453 @default.
• W2126456089 cites W1991161040 @default.
• W2126456089 cites W2013310179 @default.
• W2126456089 cites W2017426710 @default.
• W2126456089 cites W2029140175 @default.
• W2126456089 cites W2055096484 @default.
• W2126456089 cites W2063151549 @default.
• W2126456089 cites W2063443647 @default.
• W2126456089 cites W2083381199 @default.
• W2126456089 cites W2087789109 @default.
• W2126456089 cites W2093404711 @default.
• W2126456089 cites W2097175728 @default.
• W2126456089 cites W2102619694 @default.
• W2126456089 cites W2105545925 @default.
• W2126456089 cites W2106774938 @default.
• W2126456089 cites W2107176055 @default.
• W2126456089 cites W2112326496 @default.
• W2126456089 cites W2112417639 @default.
• W2126456089 cites W2116412037 @default.
• W2126456089 cites W2124985265 @default.
• W2126456089 cites W2128016314 @default.
• W2126456089 cites W2141653569 @default.
• W2126456089 cites W2142952635 @default.
• W2126456089 cites W2146495977 @default.
• W2126456089 cites W2151562469 @default.
• W2126456089 cites W2163106706 @default.
• W2126456089 cites W2167155938 @default.
• W2126456089 cites W2180502603 @default.
• W2126456089 doi "https://doi.org/10.1093/database/bau076" @default.
• W2126456089 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4105710" @default.
• W2126456089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25052703" @default.
• W2126456089 hasPublicationYear "2014" @default.
• W2126456089 type Work @default.
• W2126456089 sameAs 2126456089 @default.
• W2126456089 citedByCount "88" @default.
• W2126456089 countsByYear W21264560892014 @default.
• W2126456089 countsByYear W21264560892015 @default.
• W2126456089 countsByYear W21264560892016 @default.
• W2126456089 countsByYear W21264560892017 @default.
• W2126456089 countsByYear W21264560892018 @default.
• W2126456089 countsByYear W21264560892019 @default.
• W2126456089 countsByYear W21264560892020 @default.
• W2126456089 countsByYear W21264560892021 @default.
• W2126456089 countsByYear W21264560892022 @default.
• W2126456089 countsByYear W21264560892023 @default.
• W2126456089 crossrefType "journal-article" @default.
• W2126456089 hasAuthorship W2126456089A5002656480 @default.
• W2126456089 hasAuthorship W2126456089A5015346451 @default.
• W2126456089 hasAuthorship W2126456089A5026407317 @default.
• W2126456089 hasAuthorship W2126456089A5040021244 @default.
• W2126456089 hasAuthorship W2126456089A5046342878 @default.
• W2126456089 hasAuthorship W2126456089A5055755552 @default.
• W2126456089 hasAuthorship W2126456089A5056481154 @default.
• W2126456089 hasAuthorship W2126456089A5066100182 @default.
• W2126456089 hasAuthorship W2126456089A5066983733 @default.
• W2126456089 hasAuthorship W2126456089A5074063240 @default.
• W2126456089 hasAuthorship W2126456089A5079464681 @default.
• W2126456089 hasBestOaLocation W21264560891 @default.
• W2126456089 hasConcept C104317684 @default.
• W2126456089 hasConcept C105580179 @default.
• W2126456089 hasConcept C141231307 @default.
• W2126456089 hasConcept C142575336 @default.
• W2126456089 hasConcept C145059251 @default.
• W2126456089 hasConcept C150194340 @default.
• W2126456089 hasConcept C197077220 @default.
• W2126456089 hasConcept C22667442 @default.
• W2126456089 hasConcept C41008148 @default.
• W2126456089 hasConcept C51679486 @default.
• W2126456089 hasConcept C54355233 @default.
• W2126456089 hasConcept C70721500 @default.
• W2126456089 hasConcept C77088390 @default.
• W2126456089 hasConcept C86803240 @default.
• W2126456089 hasConcept C89604277 @default.
• W2126456089 hasConcept C91779695 @default.
• W2126456089 hasConceptScore W2126456089C104317684 @default.
• W2126456089 hasConceptScore W2126456089C105580179 @default.
• W2126456089 hasConceptScore W2126456089C141231307 @default.
• W2126456089 hasConceptScore W2126456089C142575336 @default.

• next