FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126466996> ?p ?o ?g. }

• W2126466996 endingPage "383" @default.
• W2126466996 startingPage "383" @default.
• W2126466996 abstract "To evaluate the histologic characteristics of paranasal sinus mucosa of a disease control population and children with chronic rhinosinusitis and cystic fibrosis (CRS/CF) (1) to determine whether goblet cell (GC) hyperplasia and/or submucosal gland (SMG) hyperplasia occur in pediatric CRS/CF and (2) to compare expression and localization of MUC5AC and MUC5B mucins in the sinus mucosa of both cohorts.Histologic and morphometric analyses of paranasal sinus mucosa were used to quantify the number of GCs and mucin-expressing cells. Digital imaging was used to evaluate the SMG area. Immunohistochemistry was performed to identify the cellular localization of MUC5AC and MUC5B mucins, and confocal microscopy was used to determine whether MUC5AC and MUC5B mucins were expressed in the same secretory cells.Children's National Medical Center, Washington, DC.Twenty-one children with CRS/CF who underwent endoscopic sinus surgical procedures and 18 children who underwent craniofacial resection or neurosurgical procedures for abnormalities other than sinusitis.A statistically significant increased area (4.4-fold) of SMGs was detected in the sinus mucosa of patients with CRS/CF compared with the controls (P = .02). Neither GC hyperplasia nor increased expression of MUC5AC was observed in the CRS/CF group. MUC5AC was expressed only in a subpopulation of GCs in both cohorts, and MUC5B was expressed in a subpopulation of GCs as well as in SMGs. There was a positive trend toward increased glandular MUC5B expression in the CRS/CF cohort. Colocalization of MUC5AC and MUC5B expression was observed in a subset of GCs.Significant SMG hyperplasia and a trend toward increased glandular MUC5B expression exist in children with CRS/CF. This suggests that SMG hyperplasia and glandular MUC5B mucin contribute to mucus overproduction in the sinus mucosa of this population." @default.
• W2126466996 created "2016-06-24" @default.
• W2126466996 creator A5006639931 @default.
• W2126466996 creator A5009700574 @default.
• W2126466996 creator A5013611647 @default.
• W2126466996 creator A5050387705 @default.
• W2126466996 creator A5050924248 @default.
• W2126466996 creator A5056643989 @default.
• W2126466996 creator A5057242595 @default.
• W2126466996 creator A5075504538 @default.
• W2126466996 creator A5039312753 @default.
• W2126466996 date "2011-04-18" @default.
• W2126466996 modified "2023-09-26" @default.
• W2126466996 title "Histologic Characteristics and Mucin Immunohistochemistry of Cystic Fibrosis Sinus Mucosa" @default.
• W2126466996 cites W119806249 @default.
• W2126466996 cites W1554379134 @default.
• W2126466996 cites W1859763432 @default.
• W2126466996 cites W1875993502 @default.
• W2126466996 cites W1990187346 @default.
• W2126466996 cites W1999149478 @default.
• W2126466996 cites W2000228858 @default.
• W2126466996 cites W2020201540 @default.
• W2126466996 cites W2029586848 @default.
• W2126466996 cites W2033376592 @default.
• W2126466996 cites W2036797577 @default.
• W2126466996 cites W2037261076 @default.
• W2126466996 cites W2040891540 @default.
• W2126466996 cites W2059198464 @default.
• W2126466996 cites W2081573208 @default.
• W2126466996 cites W2093670678 @default.
• W2126466996 cites W2094438822 @default.
• W2126466996 cites W2109814336 @default.
• W2126466996 cites W2163633890 @default.
• W2126466996 cites W2166433018 @default.
• W2126466996 cites W2166811167 @default.
• W2126466996 cites W2327338232 @default.
• W2126466996 cites W2332438726 @default.
• W2126466996 cites W2345551155 @default.
• W2126466996 cites W2410370970 @default.
• W2126466996 cites W2413603673 @default.
• W2126466996 cites W3106798016 @default.
• W2126466996 doi "https://doi.org/10.1001/archoto.2011.34" @default.
• W2126466996 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4148020" @default.
• W2126466996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21502478" @default.
• W2126466996 hasPublicationYear "2011" @default.
• W2126466996 type Work @default.
• W2126466996 sameAs 2126466996 @default.
• W2126466996 citedByCount "20" @default.
• W2126466996 countsByYear W21264669962013 @default.
• W2126466996 countsByYear W21264669962014 @default.
• W2126466996 countsByYear W21264669962015 @default.
• W2126466996 countsByYear W21264669962016 @default.
• W2126466996 countsByYear W21264669962017 @default.
• W2126466996 countsByYear W21264669962019 @default.
• W2126466996 countsByYear W21264669962020 @default.
• W2126466996 countsByYear W21264669962021 @default.
• W2126466996 countsByYear W21264669962022 @default.
• W2126466996 countsByYear W21264669962023 @default.
• W2126466996 crossrefType "journal-article" @default.
• W2126466996 hasAuthorship W2126466996A5006639931 @default.
• W2126466996 hasAuthorship W2126466996A5009700574 @default.
• W2126466996 hasAuthorship W2126466996A5013611647 @default.
• W2126466996 hasAuthorship W2126466996A5039312753 @default.
• W2126466996 hasAuthorship W2126466996A5050387705 @default.
• W2126466996 hasAuthorship W2126466996A5050924248 @default.
• W2126466996 hasAuthorship W2126466996A5056643989 @default.
• W2126466996 hasAuthorship W2126466996A5057242595 @default.
• W2126466996 hasAuthorship W2126466996A5075504538 @default.
• W2126466996 hasBestOaLocation W21264669961 @default.
• W2126466996 hasConcept C126322002 @default.
• W2126466996 hasConcept C142724271 @default.
• W2126466996 hasConcept C179264091 @default.
• W2126466996 hasConcept C203014093 @default.
• W2126466996 hasConcept C204232928 @default.
• W2126466996 hasConcept C2776385078 @default.
• W2126466996 hasConcept C2776938444 @default.
• W2126466996 hasConcept C2777562237 @default.
• W2126466996 hasConcept C2777768476 @default.
• W2126466996 hasConcept C2778117937 @default.
• W2126466996 hasConcept C2908647359 @default.
• W2126466996 hasConcept C71924100 @default.
• W2126466996 hasConcept C99454951 @default.
• W2126466996 hasConceptScore W2126466996C126322002 @default.
• W2126466996 hasConceptScore W2126466996C142724271 @default.
• W2126466996 hasConceptScore W2126466996C179264091 @default.
• W2126466996 hasConceptScore W2126466996C203014093 @default.
• W2126466996 hasConceptScore W2126466996C204232928 @default.
• W2126466996 hasConceptScore W2126466996C2776385078 @default.
• W2126466996 hasConceptScore W2126466996C2776938444 @default.
• W2126466996 hasConceptScore W2126466996C2777562237 @default.
• W2126466996 hasConceptScore W2126466996C2777768476 @default.
• W2126466996 hasConceptScore W2126466996C2778117937 @default.
• W2126466996 hasConceptScore W2126466996C2908647359 @default.
• W2126466996 hasConceptScore W2126466996C71924100 @default.
• W2126466996 hasConceptScore W2126466996C99454951 @default.
• W2126466996 hasIssue "4" @default.
• W2126466996 hasLocation W21264669961 @default.
• W2126466996 hasLocation W21264669962 @default.

• next