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- W2126484967 endingPage "686" @default.
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- W2126484967 abstract "Poly(acrylic acid) (PAA) and poly(ethylene glycol) (PEG), four-arm, amine-terminated particles with nanometer size and spherical shape were obtained by the polymers cross-linking, via activation with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride, in a w/o emulsion. The morphology and surface charge of the final particles are strongly dependent on the molar ratio of PAA-PEG and the PAA concentration. The physicochemical characteristics correlated with the drug-loading capacity, in vitro and ex vivo release kinetics of pilocarpine hydrochloride and biocompatibility results indicate that these nanoparticles exhibit the prerequisite behavior for use as carriers of ophthalmic drugs." @default.
- W2126484967 created "2016-06-24" @default.
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- W2126484967 date "2014-02-01" @default.
- W2126484967 modified "2023-10-18" @default.
- W2126484967 title "Poly(Acrylic Acid)–Poly(Ethylene Glycol) Nanoparticles Designed for Ophthalmic Drug Delivery" @default.
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- W2126484967 doi "https://doi.org/10.1002/jps.23793" @default.
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