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- W2126501411 abstract "The immunizing abilities of alloantigens placed within the anterior chamber of the eye have been studied in inbred rats. Although intracameral inoculation of F<sub>1</sub> hybrid lymphocytes into parental strain recipients elicited both cell- and antibody-mediated immunity, a delimited interval was identified postinoculation during which the systemic cell-mediated immune response was suppressed as indicated by prolonged acceptance of orthotopic skin allografts. The prompt appearance of hemagglutinating antibodies in the serum of immunized rats followed a time course which coincided with the suppression of cell-mediated immunity and suggested that the two events are causally related. Since exposure to allogeneic antigens on lymphoid cells via the anterior chamber elicits a transient suppression in cell-mediated immunity, whereas humoral immunity is preserved, the phenomenon resembles immune deviation." @default.
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- W2126501411 date "2004-06-01" @default.
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- W2126501411 title "Site directed mutagenesis of hMLH1 exonic splicing enhancers does not correlate with splicing disruption" @default.
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- W2126501411 doi "https://doi.org/10.1136/jmg.2003.016659" @default.
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