Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126593670> ?p ?o ?g. }
- W2126593670 endingPage "30" @default.
- W2126593670 startingPage "23" @default.
- W2126593670 abstract "In vitro drug release rates from aqueous and oil solutions as well as preformed and in situ formed aqueous and oil suspensions intended for intra-articular delivery have been investigated using the rotating dialysis cell model. Using lidocaine as a model drug substance the release kinetics from aqueous and oil suspensions have been compared and the sustained release properties from such suspensions formed in situ has been evaluated. The appearance of lidocaine in the acceptor phase after instillation of preformed and in situ formed aqueous and oil suspensions into the small aqueous donor compartment applied to zero-order kinetics as long sufficient amounts of solid lidocaine remained in the donor cell. The obtained data indicate that oil solutions and oil suspensions of lidocaine possess prolonged release properties equal to or better than those of aqueous counterparts. Also the release properties of preformed aqueous and oil suspensions are identical to such suspension types formed in situ. The present in vitro model appears useful in quality control and formulation development in the field of parenteral depots." @default.
- W2126593670 created "2016-06-24" @default.
- W2126593670 creator A5030211331 @default.
- W2126593670 creator A5039258778 @default.
- W2126593670 creator A5051485793 @default.
- W2126593670 creator A5054636531 @default.
- W2126593670 date "2008-01-01" @default.
- W2126593670 modified "2023-09-25" @default.
- W2126593670 title "In Vitro Assessment of Lidocaine Release from Aqueous and Oil Solutions and from Preformed and in Situ Formed Aqueous and Oil Suspensions. Parenteral Depots for Intra-Articular Administration" @default.
- W2126593670 cites W1496089310 @default.
- W2126593670 cites W1968943209 @default.
- W2126593670 cites W1974371653 @default.
- W2126593670 cites W1986160834 @default.
- W2126593670 cites W2004137843 @default.
- W2126593670 cites W2006376028 @default.
- W2126593670 cites W2014616711 @default.
- W2126593670 cites W2015196789 @default.
- W2126593670 cites W2030816141 @default.
- W2126593670 cites W2033121188 @default.
- W2126593670 cites W2035371366 @default.
- W2126593670 cites W2043088576 @default.
- W2126593670 cites W2052306144 @default.
- W2126593670 cites W2053729182 @default.
- W2126593670 cites W2058749139 @default.
- W2126593670 cites W2064045930 @default.
- W2126593670 cites W2064366593 @default.
- W2126593670 cites W2065370364 @default.
- W2126593670 cites W2065466797 @default.
- W2126593670 cites W2077369497 @default.
- W2126593670 cites W2079087164 @default.
- W2126593670 cites W2082291447 @default.
- W2126593670 cites W2089114863 @default.
- W2126593670 cites W2114250598 @default.
- W2126593670 cites W2152949393 @default.
- W2126593670 cites W2154416862 @default.
- W2126593670 cites W2158593900 @default.
- W2126593670 cites W2161629904 @default.
- W2126593670 cites W2163386266 @default.
- W2126593670 cites W2254652023 @default.
- W2126593670 cites W4299608669 @default.
- W2126593670 doi "https://doi.org/10.1080/10717540701828657" @default.
- W2126593670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18197520" @default.
- W2126593670 hasPublicationYear "2008" @default.
- W2126593670 type Work @default.
- W2126593670 sameAs 2126593670 @default.
- W2126593670 citedByCount "18" @default.
- W2126593670 countsByYear W21265936702012 @default.
- W2126593670 countsByYear W21265936702013 @default.
- W2126593670 countsByYear W21265936702015 @default.
- W2126593670 countsByYear W21265936702019 @default.
- W2126593670 countsByYear W21265936702020 @default.
- W2126593670 countsByYear W21265936702021 @default.
- W2126593670 countsByYear W21265936702022 @default.
- W2126593670 crossrefType "journal-article" @default.
- W2126593670 hasAuthorship W2126593670A5030211331 @default.
- W2126593670 hasAuthorship W2126593670A5039258778 @default.
- W2126593670 hasAuthorship W2126593670A5051485793 @default.
- W2126593670 hasAuthorship W2126593670A5054636531 @default.
- W2126593670 hasConcept C127413603 @default.
- W2126593670 hasConcept C149556010 @default.
- W2126593670 hasConcept C178790620 @default.
- W2126593670 hasConcept C184651966 @default.
- W2126593670 hasConcept C185592680 @default.
- W2126593670 hasConcept C192562407 @default.
- W2126593670 hasConcept C2777822432 @default.
- W2126593670 hasConcept C2780149897 @default.
- W2126593670 hasConcept C42219234 @default.
- W2126593670 hasConcept C42360764 @default.
- W2126593670 hasConcept C43617362 @default.
- W2126593670 hasConcept C71924100 @default.
- W2126593670 hasConceptScore W2126593670C127413603 @default.
- W2126593670 hasConceptScore W2126593670C149556010 @default.
- W2126593670 hasConceptScore W2126593670C178790620 @default.
- W2126593670 hasConceptScore W2126593670C184651966 @default.
- W2126593670 hasConceptScore W2126593670C185592680 @default.
- W2126593670 hasConceptScore W2126593670C192562407 @default.
- W2126593670 hasConceptScore W2126593670C2777822432 @default.
- W2126593670 hasConceptScore W2126593670C2780149897 @default.
- W2126593670 hasConceptScore W2126593670C42219234 @default.
- W2126593670 hasConceptScore W2126593670C42360764 @default.
- W2126593670 hasConceptScore W2126593670C43617362 @default.
- W2126593670 hasConceptScore W2126593670C71924100 @default.
- W2126593670 hasIssue "1" @default.
- W2126593670 hasLocation W21265936701 @default.
- W2126593670 hasLocation W21265936702 @default.
- W2126593670 hasOpenAccess W2126593670 @default.
- W2126593670 hasPrimaryLocation W21265936701 @default.
- W2126593670 hasRelatedWork W2009823598 @default.
- W2126593670 hasRelatedWork W2040146024 @default.
- W2126593670 hasRelatedWork W2084503887 @default.
- W2126593670 hasRelatedWork W2748952813 @default.
- W2126593670 hasRelatedWork W2899084033 @default.
- W2126593670 hasRelatedWork W2949080510 @default.
- W2126593670 hasRelatedWork W2951261188 @default.
- W2126593670 hasRelatedWork W2951280107 @default.
- W2126593670 hasRelatedWork W2951314393 @default.
- W2126593670 hasRelatedWork W2951570289 @default.
- W2126593670 hasVolume "15" @default.