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- W2126630901 endingPage "34" @default.
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- W2126630901 abstract "The genome of the Lymantria dispar multinucleocapsid nucleopolyhedrovirus (LdMNPV) was sequenced and analyzed. It is composed of 161,046 bases with a G + C content of 57.5% and contains 163 putative open reading frames (ORFs) of >/=150 nucleotides. Homologs were found to 95 of the 155 genes predicted for the Autographa californica MNPV (AcMNPV) genome. More than 9% of the LdMNPV genome was occupied by 16 repeated genes related to AcMNPV ORF2. Readily identifiable homologs of several genes that have been reported to play important roles in the AcMNPV life cycle are not present; these include ie-2, a transcriptional transactivator, and gp64, a major envelope glycoprotein of the nonoccluded form of the virus. A number of genes lacking in AcMNPV but present in other baculoviruses were identified; these include two viral enhancing factor homologs, a second copy of a conotoxin-like gene, and a dutpase homolog. Although a single gene predicted to encode a large subunit of ribonucleotide reductase was found, two different copies of the small subunit gene were present. In addition, homologs of genes not previously reported for baculoviruses were identified, including a predicted protein with homology to DNA ligases and another that has motifs most closely related to a yeast mitochondrial helicase. Thirteen homologous regions (hrs) containing 54 repeated sequences that include 30-bp imperfect palindromes were identified. The imperfect palindromes are related to those from other baculoviruses." @default.
- W2126630901 created "2016-06-24" @default.
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- W2126630901 creator A5050542895 @default.
- W2126630901 creator A5054104853 @default.
- W2126630901 creator A5087751268 @default.
- W2126630901 date "1999-01-01" @default.
- W2126630901 modified "2023-09-27" @default.
- W2126630901 title "Sequence and Analysis of the Genome of a Baculovirus Pathogenic forLymantria dispar" @default.
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- W2126630901 doi "https://doi.org/10.1006/viro.1998.9469" @default.
- W2126630901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9887315" @default.
- W2126630901 hasPublicationYear "1999" @default.
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