Matches in SemOpenAlex for { <https://semopenalex.org/work/W2126784251> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2126784251 endingPage "58" @default.
- W2126784251 startingPage "47" @default.
- W2126784251 abstract "Mature and immature male rabbits were fed for 120 and 20 days, respectively, a commercial diet containing theobromine in amounts of 0, 0·5, 1 and 1·5 per cent. Clinical, haematological, histopathological and histoenzymological examinations were performed. Mortality, which appeared dose- and time-related was severe and rapid, mostly in the 1 and 1·5 per cent groups and was attributed to cardiac failure. Theobromine administration resulted in marked changes in thymus and testes and the severity of lesions appeared to be related to the amounts of the ingested methylxanthine. The earliest thymic alterations in immature rabbits consisted of a blurring of demarcation between cortex and medulla accompanied, in the more advanced stages, by a decreased lymphocyte density. Similar lesions were observed in mature animals which had died in the earlier phase of the study. Testicular alterations ranged from vacuolation of spermatids and spermatocytes to multinucleated cell formation and oligospermia or aspermia with extensive degeneration of tubule cells. Some necrotic and post-necrotic myocardial foci were also recorded. The increase in testicular activity of β-glucuronidase in immature rabbits compared to the untreated animals provided further evidence of an early theobromine-induced damage of the testes." @default.
- W2126784251 created "2016-06-24" @default.
- W2126784251 creator A5016032056 @default.
- W2126784251 creator A5028272132 @default.
- W2126784251 creator A5034663926 @default.
- W2126784251 creator A5057670229 @default.
- W2126784251 creator A5076446822 @default.
- W2126784251 date "1989-01-01" @default.
- W2126784251 modified "2023-10-18" @default.
- W2126784251 title "Toxic effects of theobromine on mature and immature male rabbits" @default.
- W2126784251 cites W1982189579 @default.
- W2126784251 cites W1982842650 @default.
- W2126784251 cites W1993500540 @default.
- W2126784251 cites W1999180950 @default.
- W2126784251 cites W2009248393 @default.
- W2126784251 cites W2022157661 @default.
- W2126784251 cites W2057161834 @default.
- W2126784251 cites W2076980507 @default.
- W2126784251 cites W2083836442 @default.
- W2126784251 cites W2090118356 @default.
- W2126784251 cites W2091305184 @default.
- W2126784251 cites W2148147232 @default.
- W2126784251 doi "https://doi.org/10.1016/0021-9975(89)90089-3" @default.
- W2126784251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2918109" @default.
- W2126784251 hasPublicationYear "1989" @default.
- W2126784251 type Work @default.
- W2126784251 sameAs 2126784251 @default.
- W2126784251 citedByCount "19" @default.
- W2126784251 countsByYear W21267842512012 @default.
- W2126784251 countsByYear W21267842512013 @default.
- W2126784251 countsByYear W21267842512019 @default.
- W2126784251 countsByYear W21267842512021 @default.
- W2126784251 countsByYear W21267842512022 @default.
- W2126784251 crossrefType "journal-article" @default.
- W2126784251 hasAuthorship W2126784251A5016032056 @default.
- W2126784251 hasAuthorship W2126784251A5028272132 @default.
- W2126784251 hasAuthorship W2126784251A5034663926 @default.
- W2126784251 hasAuthorship W2126784251A5057670229 @default.
- W2126784251 hasAuthorship W2126784251A5076446822 @default.
- W2126784251 hasConcept C126322002 @default.
- W2126784251 hasConcept C134018914 @default.
- W2126784251 hasConcept C142724271 @default.
- W2126784251 hasConcept C16685009 @default.
- W2126784251 hasConcept C203014093 @default.
- W2126784251 hasConcept C2777761686 @default.
- W2126784251 hasConcept C2778095195 @default.
- W2126784251 hasConcept C2779765676 @default.
- W2126784251 hasConcept C42407357 @default.
- W2126784251 hasConcept C71924100 @default.
- W2126784251 hasConcept C86803240 @default.
- W2126784251 hasConceptScore W2126784251C126322002 @default.
- W2126784251 hasConceptScore W2126784251C134018914 @default.
- W2126784251 hasConceptScore W2126784251C142724271 @default.
- W2126784251 hasConceptScore W2126784251C16685009 @default.
- W2126784251 hasConceptScore W2126784251C203014093 @default.
- W2126784251 hasConceptScore W2126784251C2777761686 @default.
- W2126784251 hasConceptScore W2126784251C2778095195 @default.
- W2126784251 hasConceptScore W2126784251C2779765676 @default.
- W2126784251 hasConceptScore W2126784251C42407357 @default.
- W2126784251 hasConceptScore W2126784251C71924100 @default.
- W2126784251 hasConceptScore W2126784251C86803240 @default.
- W2126784251 hasIssue "1" @default.
- W2126784251 hasLocation W21267842511 @default.
- W2126784251 hasLocation W21267842512 @default.
- W2126784251 hasOpenAccess W2126784251 @default.
- W2126784251 hasPrimaryLocation W21267842511 @default.
- W2126784251 hasRelatedWork W1966504330 @default.
- W2126784251 hasRelatedWork W1974041167 @default.
- W2126784251 hasRelatedWork W1979139803 @default.
- W2126784251 hasRelatedWork W2022583443 @default.
- W2126784251 hasRelatedWork W2030889776 @default.
- W2126784251 hasRelatedWork W2037631372 @default.
- W2126784251 hasRelatedWork W2040058909 @default.
- W2126784251 hasRelatedWork W2123776403 @default.
- W2126784251 hasRelatedWork W2132898409 @default.
- W2126784251 hasRelatedWork W4249176446 @default.
- W2126784251 hasVolume "100" @default.
- W2126784251 isParatext "false" @default.
- W2126784251 isRetracted "false" @default.
- W2126784251 magId "2126784251" @default.
- W2126784251 workType "article" @default.