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- W2126860360 abstract "The study of non-atopic asthma/wheeze in children separately from atopic asthma is relatively recent. Studies have focused on single risk factors and had inconsistent findings. To review evidence on factors associated with non-atopic asthma/wheeze in children and adolescents. A review of studies of risk factors for non-atopic asthma/wheeze which had a non-asthmatic comparison group, and assessed atopy by skin-prick test or allergen-specific IgE. Studies of non-atopic asthma/wheeze used a wide diversity of definitions of asthma/wheeze, comparison groups and methods to assess atopy. Among 30 risk factors evaluated in the 43 studies only 3 (family history of asthma/rhinitis/eczema, dampness/mold in the household, and lower respiratory tract infections in childhood) showed consistent associations with non-atopic asthma/wheeze. No or limited period of breastfeeding was less consistently associated with non-atopic asthma/wheeze. The few studies examining the effects of overweight/obesity and psychological/social factors showed consistent associations. We used a novel graphical presentation of different risk factors for non-atopic asthma/wheeze, allowing a more complete perception of the complex pattern of effects. More research using standardized methodology is needed on the causes of non-atopic asthma." @default.
- W2126860360 created "2016-06-24" @default.
- W2126860360 creator A5024257683 @default.
- W2126860360 creator A5042413273 @default.
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- W2126860360 date "2014-06-06" @default.
- W2126860360 modified "2023-10-16" @default.
- W2126860360 title "Risk factors for non-atopic asthma/wheeze in children and adolescents: a systematic review" @default.
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- W2126860360 doi "https://doi.org/10.1186/1742-7622-11-5" @default.
- W2126860360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4068161" @default.
- W2126860360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24963333" @default.
- W2126860360 hasPublicationYear "2014" @default.
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