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• W2126895079 abstract "Summary Sixty unpremedicated healthy adult patients were studied during induction of anaesthesia with intravenous propofol delivered by a ‘Diprifusor’ target‐controlled infusion. Bispectral index (BIS) and spectral edge frequency (SEF 95 ) were measured concurrently with the predicted blood and effect site propofol concentrations. Logistic regression was used to calculate the predicted propofol blood and effect site concentrations required to produce unconsciousness and no response to a noxious stimulus in 50% and 95% of patients and to correlate BIS with these end‐points. The Diprifusor TCI software produces anaesthesia at consistent target concentrations. Bispectral index correlates well with clinical end‐points and may be useful during propofol anaesthesia." @default.
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• W2126895079 date "2002-03-01" @default.
• W2126895079 modified "2023-10-02" @default.
• W2126895079 title "Propofol effective concentration 50 and its relationship to bispectral index" @default.
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• W2126895079 doi "https://doi.org/10.1046/j.0003-2409.2001.02446.x" @default.
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